sdhD
mL0698c
Probable succinate dehydrogenase (hydrophobic membrane anchor protein) SdhD (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 836442 – 836933
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0698c_sdhD_dna
GATGAGCAACTCCGATCTTCAGCTCAGACCTCAAGTTCAACCTACATGCCAAAAAGGCCAGTTAGCCCCGGTGCGGCAGCGCAGCTACGACCGCCCCGCAAGCTTAGACAACCCTCGTTCACCGCGTCGACGCGCCGGCATCCCCAACTTCGAAAAGTTCGCCTGGCTGTTCATGCGGTTCTCGGGTGTCGCGCTGGTGGTACTGGCGTTCGGGCACTTATTCATCATGCTGATGTGGGACAACGGCGTGTACCGCATCGACTTCAACTTTGTGGCGCAGCGCTGGTCTTCACCGTTCTGGCGATTCTGGGACCTGGCACTACTGTGGCTGGCGCAAGTCCACGGCGGCAACGGCTTGCGCAACATCATCGACGACTACAGCCGCAAAGACCACACGCGGTTCTGGCTCAATAGCTTGCTGCTGTTGTCAATGGGGTTCACGCTGGTGCTGGGCAGCTACGTGCTGTTGTCATTCGATCCCAACATCTCCTG

Protein Sequence 

>ML0698c_SdhD_protein
DEQLRSSAQTSSSTYMPKRPVSPGAAAQLRPPRKLRQPSFTASTRRHPQLRKVRLAVHAVLGCRAGGTGVRALIHHADVGQRRVPHRLQLCGAALVFTVLAILGPGTTVAGASPRRQRLAQHHRRLQPQRPHAVLAQ_LAAVVNGVHAGAGQLRAVVIRSQHLL

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding SdhD with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

20 show intermediate predicted evidence for PPIs

129 show weak predicted evidence for PPIs

View all pooled AlphaFold results for SdhD

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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