sdhC
mL0699c
Probable succinate dehydrogenase (cytochrome B-556 subunit) SdhC (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 836930 – 837391
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0699c_sdhC_dna
GGTGAGGACAACGGCGACACCCGCGAATCCGGCTACATCGAGACCAGTAGCAGCATCATCGCGCAGACGGCGACCACCCACGACCACATACCGGGGAGATCCCGGTATGTGGTCGTGGGTGCTGCATCGTATCAGCGGCGCGACCATTTTCTTCTTCCTATTCGTCCACGTACTGGACGCTGCGATGTTGCGAGTGAACCCGCAGACCTACAACGCGGTGCTTTCTACCTACAAGGCCCCGATCGTCGGCTTCATGGAGTATGGCCTGGTGGCCGCGGTGGGATTCCACGGGTTGAACGGGATCCGGGTCATCCTGATCGACTTCTGGTCTGAAGGCCCCCGCCACCAGCGGTTGATGCTGTGGATCATCAGCGTCATCTTCTTGCTGCTCTTGGTCCCAGCCGGAGTGGTAATTGGCATACACATGTGGGAACACTTCCGAATGTGGGAGCACTTCCGATG

Protein Sequence 

>ML0699c_SdhC_protein
GEDNGDTRESGYIETSSSIIAQTATTHDHIPGRSRYVVVGAASYQRRDHFLLPIRPRTGRCDVASEPADLQRGAFYLQGPDRRLHGVWPGGRGGIPRVERDPGHPDRLLV_RPPPPAVDAVDHQRHLLAALGPSRSGNWHTHVGTLPNVGALPM

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding SdhC with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

8 show intermediate predicted evidence for PPIs

92 show weak predicted evidence for PPIs

View all pooled AlphaFold results for SdhC

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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