birA
mL0732
POSSIBLE BIFUNCTIONAL PROTEIN BirA: BIOTIN OPERON REPRESSOR + BIOTIN--[ACETYL-COA-CARBOXYLASE] SYNTHETASE (BIOTIN--PROTEIN LIGASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 873721 – 874545
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0732_birA_dna
TGGGTAGTGATCTACTCAAGCCGCCGCTGGATCCAGCGGCACTGCGTGCTGAGCTGATTGGGACGGGGCTCCGGTGGCGTCAACTGGACGTCGTCACGCAAACCGGTTCCACGAACGCTGACCTGTTGGCGCGGGCAGCGTCAGGCATCGACATCGACGGAGCGGTGCTTATTGCCGAGCACCAGACCGCTGGCCGCGGGCGTCACGGCCGCGGCTGGTCGGCTAGCCCTCGCACACAAATCACGATGTCGATCGGTGTGAGTATCGCTGACGTTCCGGTTGCCACGTGGGCCTGGTTGTCGCTGGCCACTGGGGTAGCGGTGCTGGACACGGTGGCCCCGTTGATTGACGTGACCGGCGTTGACGCCGGCCTCAAGTGGCCCAACGATGTTCTGGCCGGTCCACCAGGCTCCAAAGGTAAACTCGCGGGCATCCTGGCTGAGGTTGTGCGACCAGTCATCGTCGTCGGTGTGGGACTTAACGTCACGCAGGCCCCAAAAGAGGTCGACGGTCCTGGGGCTACCTCGTTGCTTGACCTTGGCGTGCCGGCACCCGATCGGGAGCAGCTGGTGTGCTGGCTGTTGCGAGAACTCGATGCGCGGGTTGGCCAGTGGCGAAGCGCCGACCCACAGTTGATGGCCGATTATCGGGCGCGTAGCCCGATAATCGGGTCACGTGTGCGTGCGGAGCTCCCCGGCGGCAAAGACGTGGTCGGAACCGTGCGCGGCATCGATGACCAGGGAAGGTTGTGCTTGAAAACAGAAGGGCCTACCAAAGGACAAACCGTCGTGATTTCGGCTGGTGACGTGGTGCATTTGCGCTAGT

Protein Sequence 

>ML0732_BirA_protein
WVVIYSSRRWIQRHCVLS_LGRGSGGVNWTSSRKPVPRTLTCWRGQRQASTSTERCLLPSTRPLAAGVTAAAGRLALAHKSRCRSV_VSLTFRLPRGPGCRWPLG_RCWTRWPR_LT_PALTPASSGPTMFWPVHQAPKVNSRASWLRLCDQSSSSVWDLTSRRPQKRSTVLGLPRCLTLACRHPIGSSWCAGCCENSMRGLASGEAPTHS_WPIIGRVAR_SGHVCVRSSPAAKTWSEPCAASMTREGCA_KQKGLPKDKPS_FRLVTWCICAS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding BirA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

14 show weak predicted evidence for PPIs

View all pooled AlphaFold results for BirA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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