purK
mL0735
Probable phosphoribosylaminoimidazole carboxylase ATPase subunit PurK (AIR CARBOXYLASE) (AIRC)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 875925 – 877244
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0735_purK_dna
TGATGGCTGTGCCGAGTAGATGCTCGCTTGGAGTTGCTCCATTGGTTGCCATGGTCGGTGGCGGTCAACTGGCTCGGATGACCCATCAAGCCGCGATCGCGCTGGGGCAGACCCTGCGGGTGTTAGCTACCGCTGCAGACGAACCCGCTGCTCAGGTCACCCCCGATGTGGTGATCGGCTCGCACACTGATCTTGAAGACCTGCGCCGCGTTGCCCTCGGAGCCGATGCGTTGACGTTCGATCACGAACACGTCCCGACTGAACTGCTGGACAAACTGGTGGCCGAAGGCATCAATGTGGCACCGTCGCCGCAAGCTCTGGTGCACGCCCAGGACAAGCTGGTCATGCGGCGGCGATTGGCGGCGCTGGGAGCTGCGATGCCTCGCTTCATGGCATTAGACAGTGTGGACGACTTGGCCGAAATCGATGCGTTCGCGCAGCGCCTTACGGGTTCGAAAGATGCCCCGATGGTGGTCAAGGCGGTCCGCGGGGGTTATGACGGCCGGGGGGTGCAGATGGTCCGCGACTCGGCACACGCCCGCGAGGTCGCCTCCGGATATCTAGTCGACGGAATGCCGGTCCTGGTTGAGGAGCGAGTGGAACTGCGTCGCGAATTGTCCGCGCTGGTAGCGCGCTCGCCGTTCGGCCAGGGTGCAGCCTGGCCAGTCGTGGAGACGGTGCAACGGGACGGGATTTGCGTTTTGGTGGTCGCACCGGCGTTGGCGTTGGCCGACGACCTGGCCTCGGCTGCGCAGCAGCTGGCGTTGCGATTGGCCGCTGAACTCGGCGTCGTCGGTGTGTTCGCGGTCGAGTTGTTCGAAACCGCCGACGGTGCTTTGCTGGTGAACGAGCTCGCAATGCGGCCGCACAACTCCGGACACTGGACAATGGACGGTGCTCGCACCAGCCAGTTCGAGCAGCATCTCCGTGCGGTGCTAGACTATCCCCTCGGCGAGACCGACGCCGTCGCGCCGGTGACCGTGATGGTTAACGTGCTAGGCGCCCCACAACCGCCGACGCTGAGTGTAGTGACTATGGATGAACGGCTACACCACCTGTTTGCGCGGATGCCCGATGCTCGGGTTCATCTTTACGACAAGGTTGAGCGTCCTGGTCGCAAGGTTGGGCACATCAATTTTCGCGGCACCGATAAAGACCGAAAAAACCCCACTAAGCTGCGTGAACGCGCTGAGTTGGCAGCGCATTGGCTATCACACGGGCAGTGGACGGATGGATGGGATCCACACCGTGCCGGCGACGATGTAGTGGAGATATCTCTCGCTTGCGGAGGACGAAACGATGCGCAGAGGCAGCGCTGAT

Protein Sequence 

>ML0735_PurK_protein
WLCRVDARLELLHWLPWSVAVNWLG_PIKPRSRWGRPCGC_LPLQTNPLLRSPPMW_SARTLILKTCAALPSEPMR_RSITNTSRLNCWTNWWPKASMWHRRRKLWCTPRTSWSCGGDWRRWELRCLASWH_TVWTTWPKSMRSRSALRVRKMPRWWSRRSAGVMTAGGCRWSATRHTPARSPPDI_STECRSWLRSEWNCVANCPRW_RARRSARVQPGQSWRRCNGTGFAFWWSHRRWRWPTTWPRLRSSWRCDWPLNSASSVCSRSSCSKPPTVLCW_TSSQCGRTTPDTGQWTVLAPASSSSISVRC_TIPSARPTPSRR_P_WLTC_APHNRRR_V__LWMNGYTTCLRGCPMLGFIFTTRLSVLVARLGTSIFAAPIKTEKTPLSCVNALSWQRIGYHTGSGRMDGIHTVPATM_WRYLSLAEDETMRRGSAD

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PurK with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

15 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PurK

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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