ML0756c
mL0756c
probable DNA methylase (MODIFICATION METHYLASE) (METHYLTRANSFERASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 897972 – 899639
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0756c_ML0756c_dna
GATGGTGATCACGTATATCGGTGCTGCCCCCGATACTTGTTCCATGACGACGTTCGCGGGCAAAACGGCCGCCTCTGCCGACAAAGTTCGCGGTGGTTATTACACGCCGGCGCCCGTTGCCCGATTTTTGGCCCGTTGGGTTCGCCAGGCGGGGCAAAAGATCCTCGAGCCATCCTGCGGCGATGGCCGAATCCTCCGCGAGATCGCTGCACTCACCACCCAGGCGCACGGTGTAGAACTGCTGGCGCATGAAGCGCGAAAGTCCCGGAAATTCTGCTCGGTCGACACCGAGAACTTCTTCACTTGGTTGAGCAAGACCCAAGTAGGCAGCTGGGACGGTGTTGCCGGAAACCCGCCCTACATCCGTTTCGGGAACTGGGCAGCCGACCAACGGGATCCGGCGCTGGAACTGATGAGGCATGTGGGCCTGCGCCCAACGAAATTGACCAATGCTTGGGTCCCGTTCGTCGTGGCAAGCACAACGCTGGTGCGCGACGGCGGGCGGGTGGGCCTAGTCGTTCCAGCAGAACTACTCCAAGTCACCTACGCGGCACAGCTGCGCGAATTTCTGCTGAGCCTCTATCGGGAGATCATCCTCGTGACCTTCGAGCGGTTGGTGTTCGACGGCATCCTGCAAGAAGTTGTATTGTTCTGCGGTGTCGTCGGTGCAGGCCCAGCGCAAATACGCACCATCAATCTCCGAGATGCAGAATCCCTTAACTCTTTAGCAGAGTCGAACCTGGGCGTCGAGTCTGCTCCGGCGCTGCTGCACGAAAAAGAAAAGTGGACCAAATACTTACTCGACCCCGCGCAAATCCGATTGCTACGAAAACTCAAGCATGCCAACGCGATGACCCGGTTTGGCGAAGTGGCCGATGTGGATGTGGGCATTGTTACCGGCCGCAACAGCTTCTTCACCTTCACCGACGCCGATGCGCATGCCCTAAAGCTACGCAAGCACTGCGTACCGCTCGTCTCTCGCAGTACCCAGCTGGCCGGCATCGTCTACGACACGAACTGCCGGGCCAACGATATCGCCGCCAAGCACCGGACTTGGCTGCTCGACGCCCCGCACCACCCGACAGATTCTGCCCTGGTCACACACATCGACGCAGGTAAGCGCGCCGGCGTGGATAAGGGCTACAAATGCTCCATTCGCAAGCCATGGTGGAGCACACCGTCGCTGTGGATTCCCGACCTGTTCATGCTGCGCCAAATCCACCTAGCGCCGCGGCTGACCGTCAACGCCGCCGCCGCAACCAGCACCGACACCGTGCATCGGGTCCGCCTTATCGCCGACGTTGACCCGACCGCTCTTGCCGCAGTGTTCCACAACAGCGCCACCTTCGCCTTTGCCGAGATCATGGGGCGCAGTTACGGTGGAGGCATTTTAGAGCTCGAACCCCGGGAAGCCGAGCAGCTGCCCATTCCCCCACCGGCATATGCCAGCACCGAACTTGGCCAAGACATCGATCTGCTACTGAAGGCTAACGAGATCGAAAAGGCACTCGACATCGTGGATCGCCGGGTGCTGATCGACGGACTAGGCTTGTCGCCGGACCTTGTCGCTCAATGTCGCACGGCTTGGGCATCACTGCGCGATCGCAGAACCAAGCGGGGATCCCGGGTGAACATCTCGCGACGACCATTCGACAGTCCGCCATCGTA

Protein Sequence 

>ML0756c_ML0756c_protein
DGDHVYRCCPRYLFHDDVRGQNGRLCRQSSRWLLHAGARCPIFGPLGSPGGAKDPRAILRRWPNPPRDRCTHHPGARCRTAGA_SAKVPEILLGRHRELLHLVEQDPSRQLGRCCRKPALHPFRELGSRPTGSGAGTDEACGPAPNEIDQCLGPVRRGKHNAGARRRAGGPSRSSRTTPSHLRGTAARISAEPLSGDHPRDLRAVGVRRHPARSCIVLRCRRCRPSANTHHQSPRCRIP_LFSRVEPGRRVCSGAAARKRKVDQILTRPRANPIATKTQACQRDDPVWRSGRCGCGHCYRPQQLLHLHRRRCACPKATQALRTARLSQYPAGRHRLRHELPGQRYRRQAPDLAARRPAPPDRFCPGHTHRRR_ARRRG_GLQMLHSQAMVEHTVAVDSRPVHAAPNPPSAAADRQRRRRNQHRHRASGPPYRRR_PDRSCRSVPQQRHLRLCRDHGAQLRWRHFRARTPGSRAAAHSPTGICQHRTWPRHRSATEG_RDRKGTRHRGSPGADRRTRLVAGPCRSMSHGLGITARSQNQAGIPGEHLATTIRQSAIV

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML0756c with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

31 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML0756c

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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