manA
mL0765
probable mannose-6-phosphate isomerase ManA (PHOSPHOMANNOSE ISOMERASE) (PHOSPHOMANNOISOMERASE) (PMI) (PHOSPHOHEXOISOMERASE) (PHOSPHOHEXOMUTASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 907184 – 908416
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0765_manA_dna
TGGAACTGCTACGCGGAGCGTTGCGGACATATGCGTGGGGATCGCGGACCGCTATCGCCGAATTCACTGGAAGACCTGTGCCGGCTGCTCACCCTGAAGCTGAGCTCTGGTTCGGTGCGCACCCCGGTGACTCGGTTTGGCTACAAGCAGCGAACGGCGAAACTTCGCTACTGGAGGCTCTGGTCGCTGATCCGGAAGGGCAGCTTGGCTCAGTGTCCCGCGCTCGATTTGGTGACGTGCTGCCGTTCCTGGTCAAGGTGCTGGCAGCTGACGAACCGCTGTCGCTGCAGGCCCATCCGAGCACCAAGCAGGCGGTCGAGGGTTACCTGCGCGAAGAACGTCTGGGCATTCCGGTGTCCTCGCCGGAACGTAACTACCGGGATACCAGTCACAAGCCGGAGTTATTGGTGGCGCTGCAGTCATTCGAGGCGTTGGCTGGATTTCGTCAGTCGTCACGCACTGCTGAGCTACTGACGGCGTTAGCCGTCTCCGACCTCGACCCTTTCATTCATTTGCTGAGCGACCAGTCCGACGCCGACGGTCTGCGTGCGCTGTTCACTACCTGGATAACCGCGCCCCAGACCGACATCGACATGCTGGTACCTGCCGTGCTGGAGGGGGCGATCGCCTACGTCAGTTCCGGAGCGACGGAGTTCCTGGCGGAAGTCAAGACGGTGATGGAACTTGGCGAGCGTTATCCCGGCGACGCCGGCGTGCTGGCATCGTTGTTGCTTAACCGCATCAGCCTCACTCCCGGCGAGGCTATCTTCTTGCCGGCCGGCAACTTGCATGCCTATTTGCGAGGTGTTGGGGTGGAGGTGATGGCTAACTCCGACAACGTGTTGCGAGGAGGCCTCACCCCCAAGCATGTCGATGTGCCTGAGCTGTTGCGGGTGCTGGATTTCAACCCAACTCCCGAGGAGGCGCTGCGCCCGCCGACCCGCTGCGAGGGTTTTGCGGTGGTTTACGAGACCCCGACCGATGAGTTCGAGGTAGCGCTATTGGCGCTCGACGGCGATTATCTGGGTCACGAGGTCGATGCGTCACCCCACGATGTGTCGCAAGGCCCACAGATCTTGTTGTGCACCGAGGGTGAAATTACGGTGCACGGCAAGTTCCAGGCACTCACCGTAGAACGCGGTATGGCTGTCTGGATGGCGGCCGACGACGGCCCGATTCGGCTGGTCGCGCAGCAACCCGCCAAGCTGTTCAGGGCAACCGTCGGTTTGTGAC

Protein Sequence 

>ML0765_ManA_protein
WNCYAERCGHMRGDRGPLSPNSLEDLCRLLTLKLSSGSVRTPVTRFGYKQRTAKLRYWRLWSLIRKGSLAQCPALDLVTCCRSWSRCWQLTNRCRCRPIRAPSRRSRVTCAKNVWAFRCPRRNVTTGIPVTSRSYWWRCSHSRRWLDFVSRHALLSY_RR_PSPTSTLSFIC_ATSPTPTVCVRCSLPG_PRPRPTSTCWYLPCWRGRSPTSVPERRSSWRKSRR_WNLASVIPATPACWHRCCLTASASLPARLSSCRPATCMPICEVLGWR_WLTPTTCCEEASPPSMSMCLSCCGCWISTQLPRRRCARRPAARVLRWFTRPRPMSSR_RYWRSTAIIWVTRSMRHPTMCRKAHRSCCAPRVKLRCTASSRHSP_NAVWLSGWRPTTARFGWSRSNPPSCSGQPSVCD

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ManA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

6 show intermediate predicted evidence for PPIs

43 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ManA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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