mtrB
mL0774
probable two-component sensory transduction histidine kinase MtrB
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 916684 – 918372
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0774_mtrB_dna
TGATCTTTAGTTCGCGGCGACGGATCCGGGGTCGCTGGGGGCGTTCGGGCCCCATGATGCGTGGCATGGGCGCGTTGACTCGAGTCGTGGGTGTTGTCTGGCGCCGGTCGCTGCAACTGCGAGTTGTAGCACTAACATTTGGTCTTTCGTTGGCCGTGATTTTGGCGCTTGGCTTCGTGCTCACCAGTCAGCTCACCAGCCGTGTCCTCGACGTCAAAGTCAGGGTAGCCATCGAGCAGATCGAGCGGGCACGCACCACCGTCACAGGGATCGTCAACGGTGAGGAGACCCGTTCGCTGGACAGCAGTCTGCAGCTGGCCCGCAACACGTTGACATCGAAAACTGACCCAACTTCTGGTGCTGGCCTCGTCGGTGCCTTCGATGCAGTGCTGATAGTGCCCGGTGATGGCCCGCGCACCGCGACCACGGCCGGACCCGTCGATCAGGTGCCTAATTCGTTGCGTGGCTTTATCAAAGCCGGGCAGGCGGCTTACCAGTACGCAACTGTACATACTGAAGGCTTCTCGGGGCCAGCGCTGATCATCGGCACGCCGACGTCGTCGCAGGTGACCAATCTCGAGCTTTATCTGATCTTTCCGCTGAAGAACGAACAGGCGACCGTCACGCTGGTGCGTGGCACGATGGCCACCGGTGGCATGGTGCTGCTGGTATTGCTGTCGGGTATTGCGTTGCTGGTATCGCGCCAGGTAGTGGTACCGGTGCGATCCGCGTCGCGGATCGCCGAACGGTTCGCCGAGGGGCACCTGTCGGAACGGATGCCGGTGCGTGGCGAGGACGACATGGCCCGGTTGGCGGTGTCGTTCAACGACATGGCGGAGAGCTTGTCTCGGCAGATCACCCAGCTCGAGGAATTCGGTAACCTACAACGCCGTTTTACGTCCGACGTCAGCCACGAACTCCGCACGCCGCTGACCACCGTGCGGATGGCCGCCGACTTGATCTACGACCACAGCTCCGATCTCGATCCTACGTTGCGGCGGTCCACCGAACTGATGGTCAGCGAACTCGATCGATTCGAGACACTGCTCAACGACCTGCTCGAGATCTCGCGGCACGACGCCGGCGTGGCCGAACTCTCTGTCGAGGCGGTTGATTTGCGCGTGATGGTGAATAACGCGCTGGGCAATGTCGGCCACTTGGCCGAGGAGGCCGGTATTGAACTGCTGGTGGACATGCCTGTCGACGAGGTGATTGCCGAGGTTGATGCCCGCCGAGTCGAGCGGATCTTGCGCAACCTTATCGCCAACGCTATCGACCACTCCGAGCATAAACCGGTGAGGATTCGTATGGCCGCCGACGAAGATACTGTCGCTGTCACTGTGCGTGACTACGGGATCGGACTGCGGCCCGGCGAAGAGAAGTTGGTGTTCAGTCGGTTTTGGCGTTCGGACCCGTCACGGGTGCGGCGCTCCGGCGGTACCGGCCTGGGACTGGCGATCAGCATCGAGGATGCGCGGCTGCACCAGGGTCGACTCGAAGCATGGGGCGAGCCTGGCCAGGGCGCCTGCTTCAGACTGACGCTTCCGTTGGTTCGCGGCCACAAGGTCACCACAAGTCCGCTGCCCATGAAACCGATTCTGCAACCAAGTCCGCAGGCCAGCACAGCTGGCCAACAACACGGCACCCAACGCCAACGCCTGCGAGAGCACGCTGAGAGGAGCCGGTGAT

Protein Sequence 

>ML0774_MtrB_protein
SLVRGDGSGVAGGVRAP_CVAWAR_LESWVLSGAGRCNCEL_H_HLVFRWP_FWRLASCSPVSSPAVSSTSKSG_PSSRSSGHAPPSQGSSTVRRPVRWTAVCSWPATR_HRKLTQLLVLASSVPSMQC__CPVMARAPRPRPDPSIRCLIRCVALSKPGRRLTSTQLYILKASRGQR_SSARRRRRR_PISSFI_SFR_RTNRRPSRWCVARWPPVAWCCWYCCRVLRCWYRAR_WYRCDPRRGSPNGSPRGTCRNGCRCVARTTWPGWRCRSTTWRRACLGRSPSSRNSVTYNAVLRPTSATNSARR_PPCGWPPT_STTTAPISILRCGGPPN_WSANSIDSRHCSTTCSRSRGTTPAWPNSLSRRLICA_W_ITRWAMSATWPRRPVLNCWWTCLSTR_LPRLMPAESSGSCATLSPTLSTTPSINR_GFVWPPTKILSLSLCVTTGSDCGPAKRSWCSVGFGVRTRHGCGAPAVPAWDWRSASRMRGCTRVDSKHGASLARAPASD_RFRWFAATRSPQVRCP_NRFCNQVRRPAQLANNTAPNANACESTLRGAGD

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding MtrB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

71 show weak predicted evidence for PPIs

View all pooled AlphaFold results for MtrB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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