secA1
mL0779
PROBABLE PREPROTEIN TRANSLOCASE SECA1 SUBUNIT
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 921723 – 924545
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0779_secA1_dna
TGCTGTCGAAGTTGCTGCGCCTTGGAGAAGGTCGCATAGTCAAGCGCCTCAAAAGGGTGGCCGAATATGTCAACACGTTGTCCGATAATGTCGAGAAACTCACCGATGTTGAGCTGAAGGCCAAGACCGACGAATTCAAGCAGCGGCTGGCCGACGAGAAAAACCCAGAAAGCCTCGACGATCTACTACCCGAAGCATTTGCGGTGGCCCGCGAAGCTGCTTGGCGGGTGCTCGACCAGCGTCCGTTTGACGTGCAGGTGATGGGCGGGGCGGCGTTGCACTTGGGGAACGTTGCGGAAATGAAGACCGGTGAAGGCAAGACCCTGACCTGCGTGCTGCCCGCCTACCTCAACGCGCTGGCCGGCAAGGGTGTGCATATCGTCACCGTTAACGACTACCTGGCAAAACGCGACAGCGAGTGGATGGGCCGGGTGCACCGCTTCCTGGGTCTGCAGGTCGGTGTGATCTTAGCATCCATGACCCCCGACGAGCGTAGGGTGGCCTATAACGCAGATATTACCTACGGCACCAACAATGAGTTCGGCTTCGACTACCTGCGCGACAACATGGCGCACTCGCTGGACGACTTGGTGCAGCGTGGGCACAGCTACGCCATCGTCGACGAGGTGGACTCCATCCTGATCGACGAGGCTCGCACCCCGTTGATCATTTCCGGTTCCGCCGATGGAGCGTCCAACTGGTACACCGAGTTTGCCCGGTTGGTGCGGTTGATGGACAAGGACGTTCACTACGAGGTCGACTTACGCAAACGCACCGTCGGCGTGCACGAAAAGGGCATGGAGTTCGTCGAAGACCAGCTCGGCATAGACAACCTCTACGAGGTCGCCAATTCGCCACTAGTCAGCTACCTCAACAACGCCTTGAAGGCCAAGGAGCTGTTCAACCGCGACAAGGACTACATCGTACGCGACGGCGAAGTGTTGATCGTCGACGAGTTCACCGGTCGCGTGTTGATTGGACGTCGCTACAATGAGGGCATGCACCAGGCCATCGAGGCCAAGGAGCACGTCGAGATCAAGGCTGAGAACCAGACGTTGGCCACCATCACGCTGCAGAACTATTTCCGACTCTACGACAAACTAGCCGGCATGACTGGTACCGCCCAGACCGAGGCGGCTGAGCTGCACGAGATCTACAAGCTGGGCGTGGTCGCCATTCCGACCAACAAGCCGATGATCCGCGAAGACCGATCTGACCTCATTTATAAGACTGAGGAAGCTAAATACATGGCGGTGGTCGATGACGTTGCCGAGCGTTACGAGAAGGGCCAGCCGGTGCTGATCGGCACAACCAGCGTGGAACGCTCGGAGTATCTGTCGCGGCAGTTCACCAAGCGGCACATCCCGCACAACGTGCTCAACGCCAAGTACCACGAACAAGAGGCGGGCATCGTCGCTGTGGCGGGTCGGCGCGGTGGTGTCACCGTCGCCACCAATATGGCCGGCCGGGGTACCGATATCGTGTTGGGTGGCAACGTCGACTTCCTTACCGACCAGCGATTGCGCAGACGTGGCCTGGATCCGGTGGAGACGCCGGACGAGTACGAGCAGGCCTGGCACTCCGAACTGCCCAAGGTCAAGGAGGAGGCTGGTCAAGAGGCTGCCGAGGTGATTGAGGCCGGTGGCCTGTATGTGTTGGGCACCGAACGCCACGAGTCACGGCGCATCGACAACCAGCTGCGCGGCCGCTCCGGTCGCCAAGGTGACCCCGGCGAGTCACGCTTCTACTTGTCGCTGGGTGATGAGCTCATGCGCCGGTTTCACGGCGCTACTTTGGAAGCCTTGTTGACCAGGCTGAACCTGCCCGACGATGTGCCGATCGAAGCCAAGATGGTCACCCGGGCGATCAAGAGCGCCCAGACCCAAGTCGAGCAGCAGAATTTTGAGGTCCGCAAGAATGTTCTTAAGTACGACGAGGTGATGAACCAGCAGCGTAAGGTGATCTATGCTGAGCGTCGTCGCATCCTCGAAGGTGAGAGCCTACAGCAGCAGGCGTTGGGCATGGTTCGCGACGTCATCACTGCCTACATCGACGGTGCGACTACCGACAGCTACGTCGAGGACTGGGATCTGGATGCTTTGTGGTCGGCGCTGGGGACGCTTTATCCGGTCGGGATCAAGCACGAGTCGCTGACGCACGCAGACGAGGACTCCGAGTGTGACGAGCTCAGCCGCGACGAATTGCTCGAGGCGCTGCTTATAGATGCCCAACATGCTTATGCCGCAAGGGAAGCCGAGCTCGCGGAACTGGCCGGCGAGGGTGCGATGCGTCAGTTGGAACGCAATGTGTTGCTTAACGTCGTTGACCGCAAGTGGCGCGAACACCTCTACGAGATGGATTATCTCAAGGAGGGCATTGGGCTGCGCGCGATGGCCCAGCGCGATCCGTTAGTGGAGTACCAGCGCGAGGGCTACGACATGTTCATGGCCATGCTCGATGGCGTGAAAGAGGAGTCGGTCGGCTTCTTATTCAATCTTGCTGTGGAGGCGGTGCCTGCTTCCCATGTGGCTCCGGTGGAAATACCCGAAGGGTTCACCGGATTGGTCGCGGATGTCGAGGCCATCCGACCGCGCGAAGAGGCTTCAAGCGCGTTGCGCACCAAGGATATTGATAACGAGTCGACCGGGCTGACGTATTCTGGGCCGTCCGAAGACGGCTCGACACAGGTGCAGCTTAACAGCGGCGGTGGGCAGAAAACGCCAGCCGGGATCCCGGTTGGGGCCAGTCGACGTGAGCGGCGCGAAGCTGCGCGGCGGCGAGGCCGCGGTGCCAAGCCGTCGAGATCGGTGAAAAAACGATAGC

Protein Sequence 

>ML0779_SecA1_protein
CCRSCCALEKVA_SSASKGWPNMSTRCPIMSRNSPMLS_RPRPTNSSSGWPTRKTQKASTIYYPKHLRWPAKLLGGCSTSVRLTCR_WAGRRCTWGTLRK_RPVKARP_PACCPPTSTRWPARVCISSPLTTTWQNATASGWAGCTASWVCRSV_S_HP_PPTSVGWPITQILPTAPTMSSASTTCATTWRTRWTTWCSVGTATPSSTRWTPS_STRLAPR_SFPVPPMERPTGTPSLPGWCG_WTRTFTTRSTYANAPSACTKRAWSSSKTSSA_TTSTRSPIRH_SATSTTP_RPRSCSTATRTTSYATAKC_SSTSSPVAC_LDVATMRACTRPSRPRSTSRSRLRTRRWPPSRCRTISDSTTN_PA_LVPPRPRRLSCTRSTSWAWSPFRPTSR_SAKTDLTSFIRLRKLNTWRWSMTLPSVTRRASRC_SAQPAWNARSICRGSSPSGTSRTTCSTPSTTNKRRASSLWRVGAVVSPSPPIWPAGVPISCWVATSTSLPTSDCADVAWIRWRRRTSTSRPGTPNCPRSRRRLVKRLPR_LRPVACMCWAPNATSHGASTTSCAAAPVAKVTPASHASTCRWVMSSCAGFTALLWKPC_PG_TCPTMCRSKPRWSPGRSRAPRPKSSSRILRSARMFLSTTR__TSSVR_SMLSVVASSKVRAYSSRRWAWFATSSLPTSTVRLPTATSRTGIWMLCGRRWGRFIRSGSSTSR_RTQTRTPSVTSSAATNCSRRCL_MPNMLMPQGKPSSRNWPARVRCVSWNAMCCLTSLTASGANTSTRWIISRRALGCARWPSAIR_WSTSARATTCSWPCSMA_KRSRSASYSILLWRRCLLPMWLRWKYPKGSPDWSRMSRPSDRAKRLQARCAPRILITSRPG_RILGRPKTARHRCSLTAAVGRKRQPGSRLGPVDVSGAKLRGGEAAVPSRRDR_KNDS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding SecA1 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

9 show intermediate predicted evidence for PPIs

75 show weak predicted evidence for PPIs

View all pooled AlphaFold results for SecA1

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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