aroA
mL0792c
probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 935509 – 936801
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0792c_aroA_dna
GGTGAGCATCGAGTCCTGGACGGCCCCCGTCGCGTCGACACCGGTGCAGGCGAACGTGACAATTCCGGGCTCTAAATCGCAAACCAACCGAGCACTGATGCTGGCAGCGCTAGCGGCAGCACAAGGCCAAGGCACCTCGACCATCGGCGGTGCACTGCGCAGCAGGGATACCGAACTAATGATTTCAGCGTTACGGACACTGGGCCTACACGTCGACGAGGCCGGCTCTGTCTTAACGGTCAACGGCCGAATTACCCCCGGCGAAGACGCTCAAGTGGACTGCGGTCTGGCCGGCACAGTATTGCGTTTTGTCCCACCGCTGGCGGCGCTGAGCGCCAACCCGGTCACCTTCGACGGCGACGAACAAGCCCGGGCCCGGCCGATCACACCGCTGCTGGATGCGCTGCGTGGTCTGGGCGTCCCCGTCGATGGCGTCGGTTTGCCTTTCCAGGTGCAAGGCAGCGGGTCAGTCGCCGGTGGCACCGTGGCCATTGACGCGTCGGCGTCCTCACAGTTCGTCTCCGGCCTGTTGTTGTGCGCAGCGTCGTTCACCCAAGGAGTGACCGTGCAGCACACCGGTTCGCCGGTACCGTCAGCTCCGCATATAGCGATGACGGTTATGATGCTGCGGCAAGCCGGTGTCCAGGTCGATGACTCGGTTGGTAACCGTTGGCAGGTGCGACCCGGTACAGTTGCGGCCCGGCACTGGGTCGTCGAGCCCGATCTCACGAACGCTGTTGCGTTCCTGGCGGCAGCAGCGGTCAGCGGCGGTACCGTGCGCATCACGGGCTGGCCAAAAACCAGTGTACAGCCCGCAGACAATATTCTGAACATCTTGTTCCGACTGAATGTCGTTGTTAATCAAACTGATTCATTCCTCGAAGTACAAGGATCGACGGTGTACGATGGCTTCGACGTCGACCTTCGCGACGTCGGTGAGCTCACGCCGTCGGTAGCAGCGCTAGCGGCACTGGCAACCCCAGGATCGGTGTCGCAACTACACGGCATCGCCCATCTGCGCGGCCACGAAACCGACCGACTCGCCGCACTGAGCACCGAAATCAACCGTCTGGGCGGCGACTGTCAGGAAACGTCCGACGGTTTGATTATCACCGCGACACCGCTGCGGCCCGGCGTCTGGCGAGCGTATGCTGATCACAGGATGGCAATGGCCGGCGCGATCGTCGGGTTGCGGGTCTCCGGAGTCGAAGTCGACGACATCGGTGCTACCCACAAGACGCTACCCCAGTTCCCACAACTGTGGGCGAACATGCTCAAGAGGTCGACCGGTTG

Protein Sequence 

>ML0792c_AroA_protein
GEHRVLDGPRRVDTGAGERDNSGL_IANQPSTDAGSASGSTRPRHLDHRRCTAQQGYRTNDFSVTDTGPTRRRGRLCLNGQRPNYPRRRRSSGLRSGRHSIAFCPTAGGAERQPGHLRRRRTSPGPADHTAAGCAAWSGRPRRWRRFAFPGARQRVSRRWHRGH_RVGVLTVRLRPVVVRSVVHPRSDRAAHRFAGTVSSAYSDDGYDAAASRCPGR_LGW_PLAGATRYSCGPALGRRARSHERCCVPGGSSGQRRYRAHHGLAKNQCTARRQYSEHLVPTECRC_SN_FIPRSTRIDGVRWLRRRPSRRR_AHAVGSSASGTGNPRIGVATTRHRPSARPRNRPTRRTEHRNQPSGRRLSGNVRRFDYHRDTAAARRLASVC_SQDGNGRRDRRVAGLRSRSRRHRCYPQDATPVPTTVGEHAQEVDRL

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding AroA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

12 show weak predicted evidence for PPIs

View all pooled AlphaFold results for AroA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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