dgt
mL0831
PROBABLE DEOXYGUANOSINE TRIPHOSPHATE TRIPHOSPHOHYDROLASE DGT (DGTPASE) (DGTP TRIPHOSPHOHYDROLASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 986477 – 987766
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0831_dgt_dna
ACTACGAAGGCTAACACGAATCAGCACGACCCTTACGACGACTTCGATCGTCAGCGGCGGGCGCATGAAGCGCCGAAGACTGCGGTTTTGCCGGGTAGCGAAGGTCAGCACCGCACTGAGTTCGCACGGGACCGGGCCCGGGTGCTTCACAGCGCAGCGCTGCGACGATTGTCGGACAAGACCCAAGTAGTGGGGCCCCACGAGGGAGACACTCCGCGCACCCGGCTGACTCATTCGTTGGAAGTGGCCCAGATCGGGCGGAGCATGGCGGTCGGGCTGGGTTGCGACCTCGACCTCGTTGAGTTGGCTGGACTGGCCCACGACATCGGCCACCCGCCATATGGGCACAACGGTGAACGGGCTCTTGATGAGGTGGCAGTAGGCTACGGCGGCTTCGAGGGCAATGCGCAGAATTTCCGAATCTTGACCAGCCTTGAGCCCAAAGTTATTGATGAACAAGGGTGTAGCGTGGGGTTGAACTTGACTCGCGCATCCCTGGACGCGGTTACCAAATATCCGTGGACTCGTGTAGGCGGGCTTGGACATGGGAGAAGCAAGTACGGTTTTTACGAGGAAGACCGCGATCCTGCGGATTGGGTCCGTGTATATGCGCCGGCGAATCGCGCATGCCTGGAAGCCCAGGTGATGGACTGGGCTGACGATGTCGCCTACTCTGTTCACGACGTTGAGGATGGCGTCGTTTCGCAACGAATAGACTTACGCGTGCTTGCTGACGAGTACGAGACTGCCGCTTTGGCCAAGCTGGGGGAGGGGGAATTCTCCTGGGTGACTGCCGATGAATTGATGGCCGCCGCGCACCGTCTGTCGGAGCTTCCTGTGGTCGCTGCGGTTGGCAAGTACGACGCTACGTTGGCATCGTCGGTCGCGCTCAAGCGATTAACCAGTGAACTGGTCGGCAGATTTGCCTCGGTCGCGATAGCGACCACACGTGCGGTGGCCGGTCCGGGTCCGTTGGTGCGCTATCAGGCTGACCTGCAGGTGCCCGATCTGGTGCGTGCCGAGGTCGCGGTACTGAAAATCTTGGCACTGCAGTTCATCATGTCCGATCCGCGGCATCTGGAAGGCCAGGCTCGGCAACGTGAGCGTATACACCGGGTAGCGAATTGGCTGTACTCCGGGGCGCCAAGCACCCTCGACCCAGTTTTTGTCACGGCGTTCACTACCGCTGTTGACGACAACGCCCGCTGGCGGGTCATCGTCGATCAGATCGCCTCGTACACCGAAGGTCGGCTGGAGCGTATCGATGCCGGTCAGGCGAGTCCATAGCAA

Protein Sequence 

>ML0831_Dgt_protein
TTKANTNQHDPYDDFDRQRRAHEAPKTAVLPGSEGQHRTEFARDRARVLHSAALRRLSDKTQVVGPHEGDTPRTRLTHSLEVAQIGRSMAVGLGCDLDLVELAGLAHDIGHPPYGHNGERALDEVAVGYGGFEGNAQNFRILTSLEPKVIDEQGCSVGLNLTRASLDAVTKYPWTRVGGLGHGRSKYGFYEEDRDPADWVRVYAPANRACLEAQVMDWADDVAYSVHDVEDGVVSQRIDLRVLADEYETAALAKLGEGEFSWVTADELMAAAHRLSELPVVAAVGKYDATLASSVALKRLTSELVGRFASVAIATTRAVAGPGPLVRYQADLQVPDLVRAEVAVLKILALQFIMSDPRHLEGQARQRERIHRVANWLYSGAPSTLDPVFVTAFTTAVDDNARWRVIVDQIASYTEGRLERIDAGQASP_Q

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Dgt with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

14 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Dgt

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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