cysK
mL0839c
PROBABLE CYSTEINE SYNTHASE A CYSK (O-ACETYLSERINE SULFHYDRYLASE A) (O-ACETYLSERINE (THIOL)-LYASE A) (CSASE A)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 996359 – 997291
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0839c_cysK_dna
TAGATGAGCATTGCTGAAGACGTCACACAACTAGTTGGTAACACGCCACTGGTCCGGCTACGCCGAGTTACCGAAGGTGCGCTGGCTGACGTTGTCGCCAAGCTGGAATCCTTCAATCCCGCCAACAGCGTGAAGGACAGGATAGGCGTGGCCATGATCGACACGGCCGAGGAAGCGGGTTTGATCAAGCCGGACACCGTCATCCTTGAGCCGACGAGCGGGAACACCGGCATCGCACTAGCTATGGTATGCGCAGCACGTGGCTACCACTGCGTGCTGACCATGCCCGAGACAATGAGCATCGAACGACGAATGTTGTTGCGAGCGTACGGCGCCGAACTCATCTTGACTCCGGGCGCCGATGGCATGTCAGGAGCCATCGCCAAGGCTGAGGAATTAGCCAAGTCCGATAAAAGGTATTTTATACCACAGCAATTCGAGAACCCAGCGAACCCAGCCATCCACGCCGCCACAACCGCCGAGGAAGTGTGGCGCGACACCGATGGCAAGGTAGACATCTTCGTTTCTGGAATCGGGACCGGAGGCACTATCACTGGTGTTGCCCGAATCATTAAAGAACGCCGGCCCGCCACGCAGTTCGTCGCCGTAGAGCCCGCCGCGTCGCCGGTGTTATCCGGTGGCCAGAAGGGTCCTCACCCCATTCAGGGCATCGGTGCTGGATTCGTCCCGTCGGTGCTGGTCCTGGACCTGGTGGACGAGATCGTTACCGTCGGCAACGAAGAAGCGCTCGACCTAGCCCGCAGACTGGCTAAGGAAGAGGGACTGCTGGTCGGCATCTCCGCAGGGGCGGCCGTTTGCGCCGCCCTGCACGTGGCCCGCCGGCCAGAGAATACAGGAAAACTGATCGTCGTCGTGCTGCCCGATTTCGGCGAGCGATATTTAAGCACGATGCTATTCGCGGACTTAGCCAAC

Protein Sequence 

>ML0839c_CysK_protein
MSIAEDVTQLVGNTPLVRLRRVTEGALADVVAKLESFNPANSVKDRIGVAMIDTAEEAGLIKPDTVILEPTSGNTGIALAMVCAARGYHCVLTMPETMSIERRMLLRAYGAELILTPGADGMSGAIAKAEELAKSDKRYFIPQQFENPANPAIHAATTAEEVWRDTDGKVDIFVSGIGTGGTITGVARIIKERRPATQFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPSVLVLDLVDEIVTVGNEEALDLARRLAKEEGLLVGISAGAAVCAALHVARRPENTGKLIVVVLPDFGERYLSTMLFADLAN

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding CysK with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

4 show weak predicted evidence for PPIs

View all pooled AlphaFold results for CysK

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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