ribF
mL0852
PROBABLE BIFUNCTIONAL FAD SYNTHETASE/RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBF: RIBOFLAVIN KINASE (FLAVOKINASE) + FMN ADENYLYLTRANSFERASE (FAD PYROPHOSPHORYLASE) (FAD SYNTHETASE)(FAD DIPHOSPHORYLASE) (FLAVIN ADENINE DINUCLEOTIDE SYNTHETASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1012138 – 1013133
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0852_ribF_dna
GGGAGCCGTAGGCTTGCGATCGTGCAGCGGTGGCGGGGACAAGACGAGATCCCCACGGATTGGGGCAGATGCGTGCTTACTATCGGGGTGTTCGATGGTGTGCACCGCGGGCACACCGAGCTTATCGCACACACGGTGCAAACTGGCCGCGCACGCAACGTGCCTACCGTGTTGATGACGTTCGACCCGCACCCGATGGAAGTGGTCTATCCAGGCAGCCACCCGGCGCAGCTGACCACGTTGACCCGACGAGCTGAACTCATCGAGGAGTTGGGCATCGACGTGTTCCTGGTGATGCCGTTCACGACCGATTTCATGAAACTCACCCCGGACCGCTACGTCCACGAGTTGCTGGTTGAACACCTGCACGTGGTGGAGGTCGTGGTGGGGGAGAACTTCACCTTCGGCAAGAAAGCGGCCGGCAACGTCATCATGTTGCGTCGGGCCGGGCAGCGGTTTGGGTTTGCGGTCGGGTCGATGTCACTGTTGTCCGAACATCGCGGTAATGAGACCGTGGCGTTCTCATCGACCTACATCCGGTCCTGTGTGGACGCCGGTGACATGATGGCGGCGACCGAAGCGCTGGGCCGCCCACACCGCGTCGAGGGGATGGTGGTCCGCGGCCAAGGCCGAGGCACTGAGCTTGGCTTTCCAACCGCGAATGTGGCTTCGCCGATGTATTCGGCCACCCCAGCCGACGGTGTCTATGCCGCGTGGTTCACCGTGCTTGGGCACGGTCCGGTGACTGGTACCGTGGTCCCAGGTGAATGCTATCAGGCCGCAGTGTCTGTCGGGACCAATCCGACTTTTTCCGGACGCACCCGCACCGTAGAGGCGTTCGTTCTCGACGCCGTCGCCGACCTGTATGGACAGCATGTAGCGCTGGACTTCGTTGGGCGCATTCGTGGGCAACGAAAATTTGACTCGGTGGCCGATTTAGTCGCCGAGATGGAGAAGGACATTGACCGGGCGCGGGCCCTGCTGGCTGATTGACTG

Protein Sequence 

>ML0852_RibF_protein
GSRRLAIVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHTELIAHTVQTGRARNVPTVLMTFDPHPMEVVYPGSHPAQLTTLTRRAELIEELGIDVFLVMPFTTDFMKLTPDRYVHELLVEHLHVVEVVVGENFTFGKKAAGNVIMLRRAGQRFGFAVGSMSLLSEHRGNETVAFSSTYIRSCVDAGDMMAATEALGRPHRVEGMVVRGQGRGTELGFPTANVASPMYSATPADGVYAAWFTVLGHGPVTGTVVPGECYQAAVSVGTNPTFSGRTRTVEAFVLDAVADLYGQHVALDFVGRIRGQRKFDSVADLVAEMEKDIDRARALLAD_L

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding RibF with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

4 show intermediate predicted evidence for PPIs

36 show weak predicted evidence for PPIs

View all pooled AlphaFold results for RibF

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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