lipA
mL0858c
Probable lipoate biosynthesis protein A LipA
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1020472 – 1021416
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0858c_lipA_dna
ACTGTGACTGTTGCGCCCGAAGACTGCCGCTTACTGCGATTAGAAGTGCGCAACGCACAGACCCCGATCGAGCGCAAGCCGCCATGGATCAAAACCCGGGCCCGCATGGGACCAGAGTACACCGCGCTAAAAAACCTGGTCCGCCGTGTTGCTCTGCACACGGTCTGCGAAGAGGCCGGTTGCCCCAACATCTTCGAATGCTGGGAAGATCGGGAAGCCACCTTTCTGATCGGTGGTGATCAGTGCACCCGCCGGTGCGACTTCTGCCAGATCGACACCGGGAAGCCGGCTGCGTTGGACCGCGACGAGCCCCGACGGGTCGCCGAGAGCGTGCAAACCATGGGGCTGCGGTATACCACCGTCACTGGGGTCGCCCGCGACGACTTGCCCGACGGCGGTGCCTGGCTGTACGCCACAACCGTGCGAGCCATTAAAGAGCTCAATCCGTCGACCGGGGTCGAACTGTTGATTCCGGACTTCAACGGGCAGCCCGCGCGACTGGCGGAAGTCTTCGACTCACGCCCACAAGTGTTGGCGCACAACGTCGAAACCGTGCCACGCATCTTTAAACGGATTCGGCCTGCTTTCACCTACCAACGCAGCCTGGACGTGCTCACTGCAGCGCGCGAGGCCGGCCTGGTCACCAAAAGCAACCTGATCCTCGGCCTAGGCGAAACCGCTGATGAGGTGCGCACTGCCCTGGCCGATTTGCGCAAAACCGGCTGCGACATCGTCACCATCACCCAATATCTGCGTCCGTCGATGCGCCACCACCCGGTCGAGCGCTGGGTCAGGCCTGAGGAGTTCGTCGAGTACACGCAATACGCCGAAGGTTTGGGCTTCTCGGGTGTGCTGGGCGGGCCGCTGGTGCGGTCATCGTATCGCGCCGGTCGGCTCTACGAGCAGGCTGCAGGCACCCGGACCGTCGGTACCTCGGTATCCCGT

Protein Sequence 

>ML0858c_LipA_protein
TVTVAPEDCRLLRLEVRNAQTPIERKPPWIKTRARMGPEYTALKNLVRRVALHTVCEEAGCPNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAALDRDEPRRVAESVQTMGLRYTTVTGVARDDLPDGGAWLYATTVRAIKELNPSTGVELLIPDFNGQPARLAEVFDSRPQVLAHNVETVPRIFKRIRPAFTYQRSLDVLTAAREAGLVTKSNLILGLGETADEVRTALADLRKTGCDIVTITQYLRPSMRHHPVERWVRPEEFVEYTQYAEGLGFSGVLGGPLVRSSYRAGRLYEQAAGTRTVGTSVSR

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding LipA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

4 show intermediate predicted evidence for PPIs

41 show weak predicted evidence for PPIs

View all pooled AlphaFold results for LipA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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