gcvT
mL0865
Probable aminomethyltransferase GcvT (Glycine cleavage system T protein)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1029024 – 1030127
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0865_gcvT_dna
ACCGATGCGCCAGAGCTTCTCAAGGGGCCGTTGGAAGACCGTCATCGCGAGCTTGGCGCGAATTTTGCCGAGTTCGGTGGCTGGCTGATGCCGGTGTCGTATGCTGGCACCGTCAGTGAACACAGCGCCACCCGTAATGCTGTGGGTCTATTTGACGTCAGCCACCTTGGTAAGGCGTTAGTTCGTGGGCCGGGTGCCGCGCAGTTCGTCAACTCCGTGCTCACCAACGACCTGGGCCGCATACGGCCAGGTAAGGCGCAATATACGTTGTGCTGCTCAGAGTCTGGTGGTGTTATCGATGACCTGATTGCCTACTACGTCGATGACGATGAGATCTTTTTGGTGTCCAATGCCGCCAATACCGCCGCGGTGGTCGACGCATTGCAGGCGGTAGTGCCGGCCGGCCTTACCATCATCAACCAGCATCGCTCCCACGCGGTGTTGGCGGTCCAGGGTCCTCGATCAACGGACGTGCTCGGCGAGCTCGGGCTGCCAACTGGGATTGATTACATGGGTTACGTCGATGCTTCCTATGCGGGAGTACCGGTGCGCGTCTGCCGCACCGGGTACACCGGCGAGCAAGGCTACGAACTGCTGCCGCCCTGGGAGTCAGCAGATGTGGTGTTCGACGCGTTGGTCGCCGCTGTGGTTGACGCACGCGGGGAGCCGGCCGGCCTGGGCGCTCGTGACACACTGCGCACCGAGATGGGTTACCCGCTGTATGGGCACGAACTTTCGCTTGACATCTCGCCGCTGCAGGCCCGGTGTGGCTGGGCGATTGGCTGGAAGAAGGATGCGTTCTTGGGCCGGGATGCGTTGCTGGCCGAGAAGGCGGCGGGGCCGCGACGGCTGTTGCGGGGCCTGCGAATGGCTGGCCGGGGAGTTTTGCGACCTGGGCTGACGGTGTGTGCTGGCGACATCCCGATCGGGGTCACCACGTCGGGGACGTTCTCGCCGACGTTGCAAGTTGGTGTCGCGTTGGCGTTGATCGACAGCGAAGCCGCGGTGCAGGACGGTCAGCAAATTATCGTCGACGTTCGTGGCCGTGCTGTCGAGTGCGAAGTGGTGCGTCCGCCCTTCATCGAAGTGAAGACCCGCTAGCCT

Protein Sequence 

>ML0865_GcvT_protein
TDAPELLKGPLEDRHRELGANFAEFGGWLMPVSYAGTVSEHSATRNAVGLFDVSHLGKALVRGPGAAQFVNSVLTNDLGRIRPGKAQYTLCCSESGGVIDDLIAYYVDDDEIFLVSNAANTAAVVDALQAVVPAGLTIINQHRSHAVLAVQGPRSTDVLGELGLPTGIDYMGYVDASYAGVPVRVCRTGYTGEQGYELLPPWESADVVFDALVAAVVDARGEPAGLGARDTLRTEMGYPLYGHELSLDISPLQARCGWAIGWKKDAFLGRDALLAEKAAGPRRLLRGLRMAGRGVLRPGLTVCAGDIPIGVTTSGTFSPTLQVGVALALIDSEAAVQDGQQIIVDVRGRAVECEVVRPPFIEVKTR_P

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding GcvT with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

22 show weak predicted evidence for PPIs

View all pooled AlphaFold results for GcvT

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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