pbpB
mL0908
Probable penicillin-binding membrane protein PbpB
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1073835 – 1075862
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0908_pbpB_dna
AGACGCGGCGACGCTCACCGCCCATGCTCGTCGCGGTCGGCACAGTTGGGGAACAGCTCCAGCACACCGCCCGTTCGGCAACCCAAGCGGCTTCGCCAACCAGAGAAAGCTAGGAAAGCCAAGGACACCAAAAAATCTCGCTCAGCAGTCGCGGCGGATGCAGTGACGGAGGGTCGTTCAGCTCGGAAGCGGCGCACCCGGCAGGTGGTCGAAATAGGAACTTACGGTCCATCTTTTATCTTCCGGCATCGGGGTGGCAACGTGGTTATCTTCGCGTTGATGCTGGTGGCGGCGACGCAGCTGTTCAACCTACAGGTTTCAAATGCCGCGGGTCTGCGTGCTCAGGCGGCCGGACAGCTCAGGGTAACTGACGTCGAAAAGGCGGTTCGCGGCAGCATAACCGACCGCAACAACGAGCAACTTGCCTTCACTATCGAATCGCGCGCGTTGACGTTTCAGCCGAAGAAAATTCGCCAGCAGCTGGAGGAAGCCAAACAGAAAACGCCATCCGCTCCTGACCCGCAGCAGCGCCTACAAGATATCGCCAAGGAGGTCGCGGGTCGGTTGAGCAACAAGCCCGACGGTCCGTCGTTGCTGAAGAAGCTGCAAAGCAACGACAGTTTCGTCTATTTGGCGCGCGCCGTCGATCCTGCCGTCGCCGAGGCGATCTCCGCCAAATATCCCGAAGTTGGTTCTGAACGGCAGGACCTGCGCCAGTATCCGGGCGGATCACTAGCGGCCAACATCGTCGGCGGCATCGACTGGGACGGGCATGGATTGCTGGGTCTTGAGGACTCCCTGGACTCCGTGTTGTCCGGAACCGACGGTTCGGTCACCTACGACCGCGGGTCCGACGGTGTGGTAATCCCGGGCAGCTACCGCAATCGGCACCGGGCGGTTAACGGCTCGACCGTCCAGCTCACCATCGACGACGACATCCAGTTCTACGTGCAGCAGCAGGTGCAGCAGGCAAAGAACTTGTCCGGTGCCCATAATGTTTCGGCCGTCGTCCTGGATGCCAAGACTGGCGAAGTACTTGCCATGGCCAACGACAACACCTTCGACCCGTCGCAAGACATTGGGCGCCAAGGTGGTAAGCAGCTGGGTAACTTGGCAGTTTCCTCGCCATTTGAGCCGGGCTCGGTGAATAAGGTCATCACCGCATCCGCGGTCATTGAATATGGGCTGTCCACTCCCGATGAGGTGCTGCAGGTTCCTGGCTCGATCCAGATGGGTGGTGTGTCCGTCCATGATGCGTGGGAGCACGGTGTGATGCCCTATACCACCACTGGAGTGTTTGGAAAGTCTTCCAACGTCGGTACGTTGATGCTGGCCCAGCGTGTCGGTCCGGAACGCTTTTACGACATGGTCCGCAAGTTCGGGTTAGGTCAACTCACCGGCGTGGGGCTGCCCGGTGAAAGCGAGGGGTTGGTACCGTCCGTCGACCAATGGTCGGGCAGCACTTTTTCGAATTTGCCTATAGGGCAAGGTCTTTCGACGACTCTACTGCAGATGACCGGAATGTATCAAGTCATTGCCAATGACGGGGTGCGGATACCGCCGCGGATCATTAAGGCTACTAACGCAGCTGACGGTACGCGGACGCAAGAACCGCGGCCGGACGGCATTCGGGTGGTGTCGCCGCAGACTGCCCAGACCGTGCGGCAGATGCTGCGCGCTGTGGTGCAAAAAGATCCGATGGGTTACCAGCAGGGTACTGGTCCCGCGGCCGGGGTGTCCGGCTATCAGATAGCCGGCAAGACAGGTACTGCGCAGCAAGTTAATCCCGCCTGCAGATGCTACTTCGACGATGTCTACTGGATTACCTTTGCTGGAATGGCTACCGTCGACAATCCCCGCTACGTCATCGGCACCATGATGGACAACCCTGAGCGCAACGCGGACGGTACGCCCGGTCACAGTGCGGCCCCACTTTTCCATAACGTCGCGGGCTGGCTGATGCAGCGTGAGAACGTGCCGCTGTCACCGGATCCGGGACCACCGTTGACGCTGCAGGCCACCTAGCGG

Protein Sequence 

>ML0908_PbpB_protein
RRGDAHRPCSSRSAQLGNSSSTPPVRQPKRLRQPEKARKAKDTKKSRSAVAADAVTEGRSARKRRTRQVVEIGTYGPSFIFRHRGGNVVIFALMLVAATQLFNLQVSNAAGLRAQAAGQLRVTDVEKAVRGSITDRNNEQLAFTIESRALTFQPKKIRQQLEEAKQKTPSAPDPQQRLQDIAKEVAGRLSNKPDGPSLLKKLQSNDSFVYLARAVDPAVAEAISAKYPEVGSERQDLRQYPGGSLAANIVGGIDWDGHGLLGLEDSLDSVLSGTDGSVTYDRGSDGVVIPGSYRNRHRAVNGSTVQLTIDDDIQFYVQQQVQQAKNLSGAHNVSAVVLDAKTGEVLAMANDNTFDPSQDIGRQGGKQLGNLAVSSPFEPGSVNKVITASAVIEYGLSTPDEVLQVPGSIQMGGVSVHDAWEHGVMPYTTTGVFGKSSNVGTLMLAQRVGPERFYDMVRKFGLGQLTGVGLPGESEGLVPSVDQWSGSTFSNLPIGQGLSTTLLQMTGMYQVIANDGVRIPPRIIKATNAADGTRTQEPRPDGIRVVSPQTAQTVRQMLRAVVQKDPMGYQQGTGPAAGVSGYQIAGKTGTAQQVNPACRCYFDDVYWITFAGMATVDNPRYVIGTMMDNPERNADGTPGHSAAPLFHNVAGWLMQRENVPLSPDPGPPLTLQAT_R

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PbpB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

3 proteins show strong predicted evidence for PPIs

7 show intermediate predicted evidence for PPIs

123 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PbpB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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