murE
mL0909
ProbableUDP-N-acetylmuramoylalanyl-D-glutamate-2%2C6-diaminopimelate ligase MurE
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1076004 – 1077596
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0909_murE_dna
ACTGAGGTGGTGGCGGTGCCGGTTAGGTTGCGCCCCAGCGCCACTGCGGGGGTGCGGCTCCCTGAGCTTGTGGCTCAGGTTGGTGCTGTGCTGGCCGACGGCCCCGGGCAGGCGGCGACTGTCCCAGACATTCCGGTGACCGGTGTGACGCTGCGGGCCCAGGAGGTGCTGTCCGGTGATCTGTTCGCTGCATTGGCTGGTGCATCCACACACGGCGCTCGGTATGCCGGCGTTGCGCTCGAACGAGGTGCTGTCGCGGTGCTTACCGACGTTGCAGGGGTCGCCGAGCTGACAGCCCAGGCCAGCAGCGTGCCGATACTCATACATCCGGAACCCCGCAGCGTGCTCGGCGGTCTTGCCGCCGCGGCATATGGACATCCCTCCAACCGGATGACGGTTGTTGGGATTACTGGAACATCGGGTAAGACGACTACCACCTATATGGTTGAGGCTGGTTTACGGGCTGGTGGGCGAGTGGTCGGGCTAGTCGGCACCATCGGCATTCGGATCGACGGTGCCGACATCCCTAGCTTTCTGACCACGCCGGAGGCTCCTGCGCTGCAGGCGATGCTCGCGGCGATGGTCGAGCGCGGTGTGGAAACCGTGGTTATGGAGGTGTCTAGTCACGCGTTGAGTCTGGGTCGGGTGGAAGGCACCCAGTTCGCAGTGGCCGGTTTCACCAATTTGTCTCGCGACCACCTCGATTTTCACCCCGACATGGAGGAGTATTTCGAAGCCAAGGCGGTGCTGTTCGATCCGCACTCGTTGCTGCGGGCTCGCACCGTCGTGGTATGCATCGACGATGACGCTGGGCGCGCGACGGCCGCCCGGGCCGGTGACGCCATCACAGTCAGCGCCCTAGGTCAACCCGCATCGTGGCGCGCGACGGACATTAGGTCACCGGGTGTCGGAGCCCAGGAGTTCACCGCCGTAGACCCCGCCGGTGTCCAGCACCGGGTCGGCATTCGGTTACCCGGCCGCTACAACGTCGCTAATTGTCTTGTCGCCCTGGCGATTCTAGACGTTGTTGGGGTGTCTCCGGAGCAGGCTTCCTTGGGGTTCCGGGACATCCGAATCCCCGGACGACTGGAACGGATCGACTGCGGCCAAGATTTTCTTGCACTGGTCGACTATGCGCACAAGCCAGGAGCGTTACACTCAGTGTTGACCGCCCTACTGCAGCCGGACCATCGGCTGGCAGTGGTGTTCGGTGCGGGGGGCGAGCGTGACCCGGGCAAGCGGGCTCCGATGGGCGAGATTGCCGCTGAGCTAGCCGATTTGGTCGTCGTGACCGATGACAACCCGCGTGGCGAGGATCCGGCGGCAATTCGTCGTGACATTCTGACCGGCACTGTCGCGGCTGGCGGTGCGGCGCAGGTCGTCGAGATTGGTGACCGGCGGGCTGCTATCCAATACGCGGTTGCTTGGGCGGGTCCTGATGACGTGGTGTTGGTGGCGGGCAAAGGTCATGAAACCGGGCAGCGGGGCGCTGCCGAGACCTGCCCCTTCGACGACCGGGTGGAGCTGGCTCGGGCGCTGCAGGTCCGTGACGCCCGACTGCTTCCTGCGCCTGGGCGAGCGTGCCAATGATCG

Protein Sequence 

>ML0909_MurE_protein
TEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGDLFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLAAAAYGHPSNRMTVVGITGTSGKTTTTYMVEAGLRAGGRVVGLVGTIGIRIDGADIPSFLTTPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDMEEYFEAKAVLFDPHSLLRARTVVVCIDDDAGRATAARAGDAITVSALGQPASWRATDIRSPGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIPGRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGEIAAELADLVVVTDDNPRGEDPAAIRRDILTGTVAAGGAAQVVEIGDRRAAIQYAVAWAGPDDVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDARLLPAPGRACQ_S

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding MurE with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

13 show weak predicted evidence for PPIs

View all pooled AlphaFold results for MurE

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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