murF
mL0910
ProbableUDP-N-acetylmuramoylalanyl-D-glutamyl-2%2C6-diaminopimelate-D-alanyl-D-alanyl ligase MurF
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1077593 – 1079146
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0910_murF_dna
ATCGACCTGACGGTTGCCCGGGTTACCGAGATCGTCGGTGGCGCGTTGGTCGATATCTCTCCCGAGGAGGCCGCCGAGCGTCGCGTCACCGGCAGCGTGGAATTTGATTCGCGGGCTGTTGGCCCCGGCGGTCTATTCCTGGCCTTGCCGGGGGCCCGCTCGGACGGACATGACCATGCTGCTTCGGCGATAGCGGCCGGTGCGGTGGCTGTGTTGGCTGCCCGGCCGGTCGGCGTTCCCGCCATCGTAGTTGCTCCTGACCCTCGCACGGGTGACGGCGGGCTGACTGGGGTGCTTGAGCACGATGCAGACGGATCGGGCGCGGCGGTGCTGGCCGCCTTGGCTAAGTTGGCCAAGGCGGTGGCCGCGGAGCTGGTAGCTGGCGGGCTGACTATCATTGGGATTACCGGATCGTCGGGGAAGACATCCACCAAAGATTTGGTGGCCGTCGTGCTGGAGTTGCTCGGTGAGGTGGTGGCGCCACCCGAGTCGTTCAACAATGAACTGGGTCATCCCTGGACAGTGTTGCGTGCAACCCGTAGCACGGACTATTTGATTCTGGAGATGTCGGCACGCCGTCCCGGTAATATTGCCGCGTTGGCGGCGATCGCCCCACCAAAGATAGGGGTTGTCCTCAACGTCGGCACTGCGCACCTAGGTGAGTTTGGCTCCCGGGAAGCCATCGCGCGAACTAAAACCGAGCTTCCGCAAGCTATTATGCAGTCCGGTGTGGTCATACTCAACGTCGATGACCCGGCGGTGGCGGCGATGGCTGACGCGACCGTGGCCCGCGTGATTCGGGTTAGTCGCGGTAGTTATAGCCATCCGGGGTCACCAAACAGCCCAGACGTTTGGACTGGTCCGGTGTCGCTCGACGAACTTGCTAGGCCGCGCTTCACGCTGCATACTCGAGATCCACGCGCCGGCGCCACCGAAATCCAACTCGGCGTGTACGGCGATCATCAGGTCGCCAACGCCTTGTGCGCGGCTGCGGTCGGACTGGAATGCGGTGCTAGCGTCGAGGAAGTGGCGGTCGCGCTTGCCGCGACAGGGCCGGTGTCGCGGCATCGGATGCAGGTGACCACGCGCGCTGACGGGGTGACGGTGATCGACGACACCTACAACGCCAACCCCGACTCGATGCGGGCCGGGCTACAGGCTTTGGCCTGGATCGCGCATGGTGGGACCCATGATAAGAACCAGCCAGGTTCTTGTGCTCGACGAAGCTGGGCGGTGTTGGGTGAGATGGCCGAGCTTGGAGAGGACTCGATAACCGAACACGATCGCATCGGCCGGCTAGCGGTGCGCTTAGATGTGTCTCGACTCGTTGTCGTGGGAGGGGGAAGGTCGATAAACGCCATGCACCGCGGAGCGGTTATGGAAGGTTCTTGGGGTTTAGAGACGGTTAATGTGGCCGACCCCGCTGCTGCCCTGACATTGTTGCGGGCTGAAGTACGACCCGGCGACGTGGTCCTGATCAAGGCGTCGCATTCGGTCGGCCTAGGAGCGCTGGCTGATGTACTGGTGGGCGACGGGGCCATCCGCCCATGAGAC

Protein Sequence 

>ML0910_MurF_protein
IDLTVARVTEIVGGALVDISPEEAAERRVTGSVEFDSRAVGPGGLFLALPGARSDGHDHAASAIAAGAVAVLAARPVGVPAIVVAPDPRTGDGGLTGVLEHDADGSGAAVLAALAKLAKAVAAELVAGGLTIIGITGSSGKTSTKDLVAVVLELLGEVVAPPESFNNELGHPWTVLRATRSTDYLILEMSARRPGNIAALAAIAPPKIGVVLNVGTAHLGEFGSREAIARTKTELPQAIMQSGVVILNVDDPAVAAMADATVARVIRVSRGSYSHPGSPNSPDVWTGPVSLDELARPRFTLHTRDPRAGATEIQLGVYGDHQVANALCAAAVGLECGASVEEVAVALAATGPVSRHRMQVTTRADGVTVIDDTYNANPDSMRAGLQALAWIAHGGTHDKNQPGSCARRSWAVLGEMAELGEDSITEHDRIGRLAVRLDVSRLVVVGGGRSINAMHRGAVMEGSWGLETVNVADPAAALTLLRAEVRPGDVVLIKASHSVGLGALADVLVGDGAIRP_D

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding MurF with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

7 show intermediate predicted evidence for PPIs

45 show weak predicted evidence for PPIs

View all pooled AlphaFold results for MurF

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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