ppdK
mL0955c
PROBABLE PYRUVATE%2C PHOSPHATE DIKINASE PPDK
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1123020 – 1124825
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0955c_ppdK_dna
CCGTTGCCCGGGCAGTCCCATAAAGAACCGCACAGGAGAGCAACATCAACACCGCGATCATTGAAGCAGGCAACGTCAGAATTGCGTTGGGCACTCAGCCTAGCTGCACCGGAATCCCCAGCATTCATGCGACACCTACTGGGAAACGCTCATGACAAAGTGGACATCACGACATCGAGCGAACATGTCGCCGCGTTCACAGAACACGCCATAGTGTTGCTGAATGGTAATGCACACCAAACGCGGGAACTCCTGGGCGGCAAGGGCTATAACATCAACGCGATGCGCCGACACCAACTGGCAGTACCCCCAGCGTTCTGCATCACCACCGAGGTCGGCGTTCGGTATTTGGCCGCTCCCACGCCGACGATGGAAGCGATCTGGAACGACGTGCTGGACCAGATGCGATGGCTGGAAGCCGAAACCTCACGCACATTTGGGTGGGGACCGCGGCCATTGCTGGTCAGCATTCGCTCCGGAGCCGTCCAATCGATGCCCGGGATGATGGACACCATTCTAAACTTAGGCATAAATGATCCCGTCGAGCAGGCACTGGCAGCGGCCAGCCCCTCGCCGATCCCCCAAACCTTTGCCCGCGACACCCGTCTGCGGTTCATACGCACGTATCGGCGCATAGTGGATCCGTTAAATCCCCCACCCGCCAATACCTATGACCAATTACGCGCGGCCATAGAGTCAATTTTCTCCTCATGGAACTCTCCTCGCGCGGTTGCTTACCGCACCCACTACGGTCTAGACGATCAGAGTGGTACAGCTGTGATTGTGCAAGCGATGGTGTTTGGCAACCAAGGCGCCTACTCGGGAGCCGGAACGTTATTTTCCCGCAATCCGATAACCAGAGAGAGTAAACTGTTCGGCGAGTGGTTGCCTGGCGGACAAGGCGACGATGTGGTGTCAGGATTGGTTGAAGTCCAGCCGATCACGTCCCTGCGTGACGAGCAACCTACTGTCTACGACGAGCTAGTGGACACCGCTGGCCGCTTGGAGCGACTGGGATCTGACGTGCAAGAGATCGAGTTCACCACCGAGGACAGCAAGTTATGGCTGCTGCAGACCCGGGTCGCGGAACGCTCGGCGCAGGTCGCGGTGCGCCTGGCGCTGCAACTGTGGCAGGAGGGGCTCATCGACGATGCCGAGGCACTGCGCCGGGTGACCCCGGTGCATGTCGAGACCGTGTTGCTACCCGTACTGCAACCGGAAAACCATTTATCTGCAACACTTTTAGCCAAAGGCACGCCCACTTGCCCGGGTGTGATATCAGGCAAGGCGTACACCGAAGTTGATGAAGCATTAGACGCTGCCGAGTCGGCCGAACAGGTTATCCTGGTGCGCGACCACACCAGGCCCGACGACGTCCTTGGCATGTTGGCATCACAGGGGGTTGTCACCGAGGTCGGCGGTGCCGCCAGTCATGCGGCAGTGGTCAGCCGCGAACTCAGCCGAGTGGCCGTAGTGGGCTGCGGCCAGGGAACCGCCGTATCGTTGGCTGGTAAGCAGATCACCGTTGACGGCGACAAAGGCGAGGTACGCCAAGGCAATCTGACACTGTCCGCGTGGTCGGAGAACGAAACGCCGGAGCTGCGCGAGCTGGCCGACATAGCACGACGTATCAGCCCACTGCGCGTGCACATGACCGAGGACCACACGAGGCTGGATGACTCGTCCGATACTGCGGTGCGCTTAGCCATAAACACTGGGCATGCCGACGTGGTGTCAGCCACCCCGCTAATCGTCATGATGACCACTCTGCGGCTGCAAGACTCAAAGGATTCAAGCGCCAAATCG

Protein Sequence 

>ML0955c_PpdK_protein
PLPGQSHKEPHRRATSTPRSLKQATSELRWALSLAAPESPAFMRHLLGNAHDKVDITTSSEHVAAFTEHAIVLLNGNAHQTRELLGGKGYNINAMRRHQLAVPPAFCITTEVGVRYLAAPTPTMEAIWNDVLDQMRWLEAETSRTFGWGPRPLLVSIRSGAVQSMPGMMDTILNLGINDPVEQALAAASPSPIPQTFARDTRLRFIRTYRRIVDPLNPPPANTYDQLRAAIESIFSSWNSPRAVAYRTHYGLDDQSGTAVIVQAMVFGNQGAYSGAGTLFSRNPITRESKLFGEWLPGGQGDDVVSGLVEVQPITSLRDEQPTVYDELVDTAGRLERLGSDVQEIEFTTEDSKLWLLQTRVAERSAQVAVRLALQLWQEGLIDDAEALRRVTPVHVETVLLPVLQPENHLSATLLAKGTPTCPGVISGKAYTEVDEALDAAESAEQVILVRDHTRPDDVLGMLASQGVVTEVGGAASHAAVVSRELSRVAVVGCGQGTAVSLAGKQITVDGDKGEVRQGNLTLSAWSENETPELRELADIARRISPLRVHMTEDHTRLDDSSDTAVRLAINTGHADVVSATPLIVMMTTLRLQDSKDSSAKS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PpdK with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

11 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PpdK

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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