pgsA3
mL0979
PROBABLE PGP SYNTHASE PGSA3 (CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3- PHOSPHATIDYLTRANSFERASE) (PHOSPHATIDYLGLYCEROPHOSPHATE SYNTHASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1147778 – 1148359
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0979_pgsA3_dna
GTAGATTGCGTCCGTATTGCCAACCTCGCCAATATCCTGACTGGCTTGCGGCTGATGTTGGTCCCCGTTTTTTTGGTTGCCTTGTTCGCTGGGAATGGCCACGAAATCGTCGGTCGGATAGCGGCTTTCGTGATCTTCACAGTTGCCTGCATTACCGATCGGTTAGACGGTTTGCTGGCCCGCCGCTACGGCATGGCGACTGAATTCGGTGCGTTCGTCGATCCGATCGCGGACAAGACCCTGATCGGGGCGGCGCTGATCGGACTTTCGATGCTTGGTGACCTGCCATGGTGGGTCACGGTGCTTATCATGACTCGCGAGCTTGGAGTGACTTTATTGCGGTTGGCTGTTATTCATCGCGGGGTCATTCCGGCAAGTTGGGGTGGCAAACTCAAGACTGTGGTCCAGGCAGTAGCGATCGGTCTGTTCCTGCTGCCTTTGACGCAACTGTCAGTGCCGTTCCACGTGGGTGCAGCAGTGGTGATGGCAGTTGCGGTCGTGCTTACGGTGGTCACGGGTGTCGACTACGTGGCTGGGACAATCAGGGCCGTCAGGGGAGTGCACCAGACAGCCAGCTGATCA

Protein Sequence 

>ML0979_PgsA3_protein
VDCVRIANLANILTGLRLMLVPVFLVALFAGNGHEIVGRIAAFVIFTVACITDRLDGLLARRYGMATEFGAFVDPIADKTLIGAALIGLSMLGDLPWWVTVLIMTRELGVTLLRLAVIHRGVIPASWGGKLKTVVQAVAIGLFLLPLTQLSVPFHVGAAVVMAVAVVLTVVTGVDYVAGTIRAVRGVHQTAS_S

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PgsA3 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

4 show intermediate predicted evidence for PPIs

64 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PgsA3

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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