dxs
mL1038
PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE SYNTHASE DXS1 (1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE) (DXP SYNTHASE) (DXPS)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1201218 – 1203149
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1038_dxs_dna
CTGGAACAGATCCGCAGGCCCGCTGATCTGCAGCATCTTTCTCAGCAGCAGCTACGGGATCTGGCTGCCGAGATCCGTGAGCTCCTCGTTCACAAGGTGGCGGCCACCGGGGGACACTTGGGGCCGAACCTGGGTGTTGTCGAACTCACGCTGGCGTTGCACCGAGTGTTCGACTCACCGCATGATCCGATTATCTTCGACACCGGTCACCAGGCGTACGTCCACAAAATGTTGACGGGACGCTGTCAGGACTTCGACAGTCTGCGTAAAAAGGCCGGGTTGTCGGGGTACCCGTCTCGCGCCGAGAGCGAACACGACTGGGTGGAGTCCAGCCACGCCAGCACGGCGTTATCGTACGCCGACGGTCTGGCTAAGGCATTCGAGCTGGCCGGAAACCGCAACCGACACGTAGTCGCGGTGGTTGGGGACGGCGCGCTTACCGGTGGTATGTGCTGGGAGGCGCTTAACAATATCGCAGCAACACCGCGTCCGGTGGTCATCGTAGTCAATGACAATGGTCGCAGTTACGCGCCCACGATTGGCGGTGTAGCCGATCACCTCGCCACGCTGCGGCTGCAGCCGGCCTACGAGCGGCTACTTGAGAAGGGGCGTGATGCACTTCACTCTTTGCCGCTGATAGGCCAGATCGCTTACCGTTTCATGCACAGTGTCAAAGCCGGTATCAAGGATTCCCTATCGCCGCAGCTGCTGTTCACCGATCTCGGGCTAAAGTATGTTGGCCCGGTTGATGGTCACGATGAACATGCGGTAGAGGTCGCGTTGCGTAAGGCCCGCGGCTTCGGTGGCCCGGTGATCGTGCACGTCGTCACCCGCAAGGGTATGGGCTATCCCCCGGCCGAAGCCGATCAAGCCGAACAGATGCACACCTGCGGCGTGATGGACCCGACGACCGGGCAACCCACCAAGATTGCTGCTCCTGACTGGACGGCGATCTTTTCCGATGCCCTCATCGGTTATGCTATGAAGCGACGTGACATTGTGGCTATTACCGCGGCTATGCCGGGCCCTACCGGTCTAACAGCGTTCGGTCAGTGTTTTCCGGATCGGTTGTTCGATGTCGGGATCGCTGAGCAACACGCGATGACGTCGGCGGCCGGGTTGGCTATGGGCAGGATGCACCCGGTGGTGGCGATCTATTCGACATTTCTCAACCGGGCGTTCGACCAGATCATGATGGACGTGGCGCTACACAAGTTGCCTGTTACCATGGTGATTGACCGGGCTGGCATTACCGGTTCGGACGGCCCCAGTCATAACGGCATGTGGGATTTGTCGATGCTAGGCATCGTACCGGGGATGCGAGTGGCCGCGCCTCGAGACGCCATTCGGTTGCGCGAAGAACTCGGTGAGGCGCTTGACGTCGACGACGGTCCGACGGCGATACGATTCCCCAAAGGAGATGTGTGTGAAGATATTCCGGCTTTGAAGCGCCGATCGGGCGTGGACGTACTCGCGGTGCCGGCTACGGGGTTGGCCCAGGACGTGCTGCTGGTGGGGGTCGGCGTTTTTGCGTCGATGGCGTTGGCGGTGGCCAAGCGGCTGCACAACCAGGGAATCGGCGTAACAGTGATTGACCCACGTTGGGTGTTGCCGGTGTGCGACGGTGTTCTCGAACTGGCGCATACCCACAAACTGATCGTCACGCTGGAGGACAACGGGGTCAATGGCGGTGTAGGCGCAGCCGTATCTACCGCGCTGCGTCAAGTGGAGATTGACACACCTTGCCGCGATGTTGGATTGCCGCAGGAGTTCTACGATCATGCTTCGCGGAGTGAGGTGTTGGCCGATTTGGGGCTGACCGACCAAGACGTCGCCCGTCGGATCACCGGCTGGGTTGTTGCATTCGGCCATTGCGGTTCCGGTGACGATGCAGGTCAGTACGGTCCGCGGAGCAGCCAAACCATGTAGCTT

Protein Sequence 

>ML1038_Dxs_protein
LEQIRRPADLQHLSQQQLRDLAAEIRELLVHKVAATGGHLGPNLGVVELTLALHRVFDSPHDPIIFDTGHQAYVHKMLTGRCQDFDSLRKKAGLSGYPSRAESEHDWVESSHASTALSYADGLAKAFELAGNRNRHVVAVVGDGALTGGMCWEALNNIAATPRPVVIVVNDNGRSYAPTIGGVADHLATLRLQPAYERLLEKGRDALHSLPLIGQIAYRFMHSVKAGIKDSLSPQLLFTDLGLKYVGPVDGHDEHAVEVALRKARGFGGPVIVHVVTRKGMGYPPAEADQAEQMHTCGVMDPTTGQPTKIAAPDWTAIFSDALIGYAMKRRDIVAITAAMPGPTGLTAFGQCFPDRLFDVGIAEQHAMTSAAGLAMGRMHPVVAIYSTFLNRAFDQIMMDVALHKLPVTMVIDRAGITGSDGPSHNGMWDLSMLGIVPGMRVAAPRDAIRLREELGEALDVDDGPTAIRFPKGDVCEDIPALKRRSGVDVLAVPATGLAQDVLLVGVGVFASMALAVAKRLHNQGIGVTVIDPRWVLPVCDGVLELAHTHKLIVTLEDNGVNGGVGAAVSTALRQVEIDTPCRDVGLPQEFYDHASRSEVLADLGLTDQDVARRITGWVVAFGHCGSGDDAGQYGPRSSQTM_L

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Dxs with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

27 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Dxs

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.