esxL1
mL1056
Putative ESAT-6 like protein EsxL1 (ESAT-6 LIKE PROTEIN 4)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1221790 – 1222077
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1056_esxL1_dna
GGAAACATTAACTACCAGTTTGGGGAGATCGACGCACATGGAGCGGCTATCCGCGCTCAAGCGGCTGCGTTGGAGACCACCCACCAGGCCATTCTAGCCACTGTGCGGGACGCCGCTGAGTTTTGGGGCGGACAAGGTTCGACTGCCCATGAAATGTTCATAGCCGACCTGGGTCGTAACTTCCAGATGATTTACGAGCAGGCCAACTCTCACGGCCAAAAGGTGCAACGCGCCAGCTCCTCCATGGCTGACACTGACCGCTCTGTCAGTTCCGCTTGGTCCTAACGT

Protein Sequence 

>ML1056_EsxL1_protein
GNINYQFGEIDAHGAAIRAQAAALETTHQAILATVRDAAEFWGGQGSTAHEMFIADLGRNFQMIYEQANSHGQKVQRASSSMADTDRSVSSAWS_R

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EsxL1 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

6 show intermediate predicted evidence for PPIs

21 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EsxL1

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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