folP2
mL1063
PROBABLE DIHYDROPTEROATE SYNTHASE 2 FOLP2 (DHPS 2) (Dihydropteroate pyrophosphorylase 2)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1228779 – 1229654
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1063_folP2_dna
CAGTCAATGCTGTGCGGCCGGCCGGTCGCAGCGGATCGCCAACTGATCATGGCGATCGTCAACCGTACCCCGGATTCGTTCTATGACCGGGGCGCGACCTTCAGTGACGAGGCTGCTCGTGCTGCAGCGCACCGGGCCGTTGCGGAGGGCGCCGATGTCATCGATGTCGGCGGCGTTAAAGCAGGGCCTGGTCAGGGCGTTGACGTAGACACCGAGATCGCCCGGTTGGTTCCGTTCATCGAATGGCTACGCAGCGCCTATACAGACCTGCTGATCAGCGTAGACACCTGGCGAGCAGAGGTAGCAAGACTGGCTTGCACTGCGGGCGCAGACCTGATCAACGACAGCTGGGGTGGAGCCGACCCGGCCATGCATGAGGTCGCCGCTGAGCTTGGCGCGGGCCTGGTGTGTTCGCACACCGGTGGCGCGCTGCCCCGCACGCGTCCCTTTCGGGTGAGTTACGGTACGACGACCCGCGGTGTGGTGGACGATGTGATTCGCCAGGTCACTGCAGCTGCCGAGCGCGCGGTCGCGGCCGGGGTAACCCGCGATTCGGTGTTGGTCGACCCGACCCACGATTTCGGCAAGAACACTTTCCACGGGCTGCTGCTGTTGCGTCATGTAGACGAACTTGTTAAGACCGGGTGGCCCGTGCTCATGTCGTTGAGCAATAAGGACTTCGTCGGGGAGACTCTGGGCGTGGGTTTGACGGAACGGCTAGAGGGTACGTTGGCGGCCACTGCGTTGGCGGCGGCAGCTGGCGTCCGCATGTTTCGGGTGCACGAGGTCGTAGCGACCAGGCGGGTTCTGGAGATGGTGGCTTCGATCCAGGGGACGCGTCCCCCAACGCGCACGGTGAGGGGACTCGCATGACGG

Protein Sequence 

>ML1063_FolP2_protein
QSMLCGRPVAADRQLIMAIVNRTPDSFYDRGATFSDEAARAAAHRAVAEGADVIDVGGVKAGPGQGVDVDTEIARLVPFIEWLRSAYTDLLISVDTWRAEVARLACTAGADLINDSWGGADPAMHEVAAELGAGLVCSHTGGALPRTRPFRVSYGTTTRGVVDDVIRQVTAAAERAVAAGVTRDSVLVDPTHDFGKNTFHGLLLLRHVDELVKTGWPVLMSLSNKDFVGETLGVGLTERLEGTLAATALAAAAGVRMFRVHEVVATRRVLEMVASIQGTRPPTRTVRGLA_R

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding FolP2 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

3 show intermediate predicted evidence for PPIs

19 show weak predicted evidence for PPIs

View all pooled AlphaFold results for FolP2

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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