tagA
mL1066
PROBABLE DNA-3-METHYLADENINE GLYCOSYLASE I TAGA (TAG I) (3-methyladenine-DNA glycosylase I%2C constitutive) (DNA-3-methyladenine glycosidase I )
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1230988 – 1231566
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1066_tagA_dna
AGCGACGATGGGCTGGTTCGCTGTGGCTGGGCGGACGTTCGATCCGGGCTCCACTGGCAGCTGTATCGCAACTATCACGACCAAGAGTGGGGCAGCCCAGTACGATGCGGAGTGGCCTTGTTCGAGCGGATGAGCCTGGAGGCCTTTCAGAGTGGTCTGTCGTGGCTGCTCATTCTGCGCAAACGGGAAAATTTCCGGCGCGCCTTCTCCGGGTTCGATATCGAAGAGGTAGCCCGTTATACCCATGCCGATGTGCAACGGTTGTTGTTCGATGACGGAATTGTGCGCAACCGCGTCAAGATCGAGGCGACAATCGCCAACGCGCGTGCGGCCGCTGAGCTGGGGTCTGCAGCAGACTTGTCTGAGTTGCTGTGGTCATTCGCCCCACAGCCGCGGTCCAGGCCCGCTGACGGATCCGAAATCCCTTCGACCAGTGCGGAAGCGAAGGCGATGGCGCGTGAATTGAAACGGCGCGGGTTCCGCTTCGTCGGGCCTACTACGGCCTATGCACTTATGCAGGCTACGGGGATGGTTGACGATCACATCTGTACTTGCTGGGTGCCTCCAACACGGTGACCC

Protein Sequence 

>ML1066_TagA_protein
SDDGLVRCGWADVRSGLHWQLYRNYHDQEWGSPVRCGVALFERMSLEAFQSGLSWLLILRKRENFRRAFSGFDIEEVARYTHADVQRLLFDDGIVRNRVKIEATIANARAAAELGSAADLSELLWSFAPQPRSRPADGSEIPSTSAEAKAMARELKRRGFRFVGPTTAYALMQATGMVDDHICTCWVPPTR_P

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding TagA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

4 show intermediate predicted evidence for PPIs

37 show weak predicted evidence for PPIs

View all pooled AlphaFold results for TagA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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