prfA
mL1134
PROBABLE PEPTIDE CHAIN RELEASE FACTOR 1 PRFA (RF-1)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1325822 – 1326907
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1134_prfA_dna
GCGCAGCCGGTGCAATCGATCGACGTGTTGCTTATCGAACACGCTGAACTTGAGCTTGCATTGGCAGACCCGGAACTGCACAGCAATCCCGCCGAGGCGCGCAAAGCCGGACGTCGGTTCGCCCGATTGGCCCCGATCGTGGCCACGCACCGCAAGCTGATATCGGCGCGCGACGATTTGCAGACCGCACGTGAACTCGCCGCCGGCGATGAGTCGTTCGCTGACGAGATCGCCGAACTGGAATCACGGATAGCCGAACTAACTACCCAACTCACTGACATGCTGGCGCCACATGACCCGCATGGCCCCGACGACATAGTGCTTGAAGTGAAATCCGGCGAGGGTGGTGAAGAGTCGGCCTTGTTCGCTGCTGACCTTGCGAGGATGTACATCCGCTACGCCGAACGGCACGGTTGGACGGTGACGGTGCTGGACGAAACCACCTCGGATCTGGGCGGCTATAAGGACGCGACGTTAGCGATTTCTCATAAGGGTGCCAGTGATGGTGACGCTGTCGACGGGGTGTGGTCGCGAATGAAGTTCGAAGGCGGGGTGCACCGGGTGCAACGGGTACCGGTAACGGAATCCCAAGGCCGTGTGCATACTTCGGCAGCGGGCGTGCTGGTCTATCCGGAACCCGAGGAAATAGGTGAAGTGCACATCGACGAGTCGGATCTGCGCATCGATGTCTACCGGTCTTCAGGCAAAGGCGGCCAAGGCGTTAATACAACCGATTCCGCGGTGCGGATCACTCATCTACCTACCGGGGTTGTTGTCACCTGTCAAAACGAACGGTCGCAGCTGCAGAACAAGACACGTGCGTTGCAGGTGTTGGCCGCCCGCCTGCAGGCAATGGCCGAGGAGCAAGCACTAGCCAACGCGTCGGCGGATCGGGCCAGCCAGATTCGCACGGTGGACCGTAGTGAACGCATTCGCACCTACAACTTCCCGGAGAACCGGATCACGGATCACCGAATCGGTTACAAGGCACACAATCTCGATCAGGTCCTAGACGGTGACCTGGATGCGCTTTTTGACGCGTTAAGTGCTGCTGATAAGCAGTCAAGGTTGCAACAGGTATGATGA

Protein Sequence 

>ML1134_PrfA_protein
AQPVQSIDVLLIEHAELELALADPELHSNPAEARKAGRRFARLAPIVATHRKLISARDDLQTARELAAGDESFADEIAELESRIAELTTQLTDMLAPHDPHGPDDIVLEVKSGEGGEESALFAADLARMYIRYAERHGWTVTVLDETTSDLGGYKDATLAISHKGASDGDAVDGVWSRMKFEGGVHRVQRVPVTESQGRVHTSAAGVLVYPEPEEIGEVHIDESDLRIDVYRSSGKGGQGVNTTDSAVRITHLPTGVVVTCQNERSQLQNKTRALQVLAARLQAMAEEQALANASADRASQIRTVDRSERIRTYNFPENRITDHRIGYKAHNLDQVLDGDLDALFDALSAADKQSRLQQV

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PrfA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

3 show intermediate predicted evidence for PPIs

47 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PrfA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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