esxL2
mL1180c
Putative ESAT-6 like protein EsxL2 (ESAT-6 LIKE PROTEIN 4)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1380303 – 1380590
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1180c_esxL2_dna
GTAATGGGAAACATTAACTACCAGTTTGGGGAGATCGACGCACATGGAGCGGCTATCCGCGCTCAAGCGGCTGCGTTGGAGACCACCCACCAGGCCATTCTAGCCACTGTGCGGGACGCCGCTGAGTTTTGGGGCGGACAAGGTTCGACTGCCCATGAAATGTTCATAGCCGACCTGGGTCGTAACTTCCAGATGATTTACGAGCAGGCCAACTCTCACGGCCAAAAGGTGCAACGCGCCAGCTCCTCCATGGCTGACACTGACCGCTCTGTCAGTTCCGCTTGGTCC

Protein Sequence 

>ML1180c_EsxL2_protein
VMGNINYQFGEIDAHGAAIRAQAAALETTHQAILATVRDAAEFWGGQGSTAHEMFIADLGRNFQMIYEQANSHGQKVQRASSSMADTDRSVSSAWS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EsxL2 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

20 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EsxL2

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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