esxK2
mL1181c
Putative ESAT-6 like protein EsxK2
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1380642 – 1380944
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1181c_esxK2_dna
AGGATGACAGCTGCACATTTTATGACCGACCCACAGGCGATGCGGGACATGGCGCGCAAATTTGACATGCACGCCCAGAACGTGCGAGACGAGTCCCACAAGATGTTCATGTCCTCGATGGACATCGCTGGTGCGGGCTGGAGTGGGACCGCCCAGTTGACCTCCCACGACACCATGGGGCAGATAAATCAGGCGTTTCGCCACATAGTGACCCTGCTGCAGGACGTGCGTGACCAGCTGGGTACCGCCGCCGATCGCTACGAGCACCAAGAAGAGAACTCGAGGAAAATCCTTTCTGGCAGC

Protein Sequence 

>ML1181c_EsxK2_protein
RMTAAHFMTDPQAMRDMARKFDMHAQNVRDESHKMFMSSMDIAGAGWSGTAQLTSHDTMGQINQAFRHIVTLLQDVRDQLGTAADRYEHQEENSRKILSGS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EsxK2 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

4 show intermediate predicted evidence for PPIs

32 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EsxK2

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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