acpS
mL1192
HOLO-[ACYL-CARRIER PROTEIN] SYNTHASE ACPS (HOLO-ACP SYNTHASE) (CoA:APO-[ACP]PANTETHEINEPHOSPHOTRANSFERASE) (CoA:APO-[ACYL-CARRIER PROTEIN]PANTETHEINEPHOSPHOTRANSFERASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1405884 – 1406276
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1192_acpS_dna
GGCATTGTCGGCGTGGGAATCGACCTCGTCTCCATCCCTGATTTCGCCGAGCAGGTCAGCCAACCGGGAACGGTGTTCATGACTATCTTCACTCCTGGTGAGCGTCGCGATGCCTCGGTCAAGAGTTCGTCGGCGGTGTGTCACCTGGCGGCGCGTTGGGCTGTGAAGGAAGCGGTGATCAAGGCGTGGTCAGGATCGCGGTTCGCCCAGCGACCGATGCTGCCAGAGAACATCCACCGCGATATCGAGGTAGTCAACGACATGTGGGGCCGTCCGCGGGTCCGGCTCACCGGAGCCATCGCTAAGCATCTGACGGATGTGACGATCCATGTGTCGCTGACGCACGAAGGGGATATCGCGGCGGCAGTGGTGATCTTGGAGGTTCTGTGAGCT

Protein Sequence 

>ML1192_AcpS_protein
GIVGVGIDLVSIPDFAEQVSQPGTVFMTIFTPGERRDASVKSSSAVCHLAARWAVKEAVIKAWSGSRFAQRPMLPENIHRDIEVVNDMWGRPRVRLTGAIAKHLTDVTIHVSLTHEGDIAAAVVILEVL_A

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding AcpS with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

4 show intermediate predicted evidence for PPIs

37 show weak predicted evidence for PPIs

View all pooled AlphaFold results for AcpS

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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