bioF
mL1217
PROBABLE 8-AMINO-7-OXONONANOATE SYNTHASE BIOF (AONS) (8-AMINO-7-KETOPELARGONATE SYNTHASE) (7-KETO-8-AMINO-PELARGONIC ACID SYNTHETASE) (7-KAP SYNTHETASE) (L-ALANINE--PIMELYL CoA LIGASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1439917 – 1441074
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1217_bioF_dna
AAGGTCCCGATCGAGACGTCACCGCTGGCCTGGCTGGAAGCAGTGGAGCAACAGCGCCGCGGGGCCGGGCTGCGCCGTTCGCTGCGGCCGCGCTCAGCCGTTGCCACCGAGCTGGATCTGGCCTCCAACGACTATCTCGGTCTCTCCCAACATCCCGACGTCATCGACGGCGGCGTTGCGGCGTTGCGGGTTTGGGGTGCAGGTGCCACCGGATCCCGCCTGGTCACCGGCGATACCATACTGCACCACGAATTGGAATGCGAGCTAGCTGAATTTGTCGGCGCCTGTGTCGGCCTACTGTTTTCTTCCGGTTATGCCGCCAACCTCGGGGCTGTTGTCGGTTTGTCCGGCCCGGGTTCGCTGATCGTCTCCGATGCCTATTCGCACGCGTCCCTGGTGGATGCTTGCCGGCTGTCGCGGGCGCGGGTGGTGGTGACACCGCACTGTGACGTTGACGCCGTGGACACCGCGCTGAGGTCATGCCACGAGGAGCGTGCGGTTGTTGTCACTGAGTCGGTGTTCAGCGCTGATGGTGTGCTGGCCCCTGTTTCGGAGTTGCACGATGTATGCCGTCGGCACGGCGCGTTGCTCCTCGTAGACGAGGCGCACGGCCTCGGTGTGCGTGGTGGTGGGCGCGGGCTGGTATACGAGGTCGGGCTGGCGGGTGCACCTGACGTGGTGATTACGACTACCATGTCCAAGGCGCTCGGCAGCCAGGGTGGTGCGGTTCTCGGGTCGTCCGCGGTGCGTGCTCACCTGATCAATACCGCCCGTCCGTTCATCTTCGACACTGGTTTGGCGCCTGCGGCGGTAGGTGCCGCGCGGGCCGCGCTGCAAATACTGAAGGCCGAGACGTGGCGCCCAGAGGCGGTGTTGCAGCACGCCCGAACCTTGGCTAAGATCTGCGATCTGTCCGAGCTGCCGCAGTCGGCGGTGGTCTCAGTAGTGTTGGGCGATCCGGAGGTAGCGTTGGCCGCCGCGATCGCCTGCCTGGACGCCGGCGTGCGGGTGGGCTGCTTCCGGCCTCCGACTGTGCCGGCCGGGACGTCGCGGCTGCGGTTGACTGCGCACGCGTCTCTCGATAGCGCTAAGTTGGAAGTGGCCCGGCGGGTGTTGACGGACGTTCTTGGTGGCTGTTGTGTGGCGCGCCGTTGACTG

Protein Sequence 

>ML1217_BioF_protein
KVPIETSPLAWLEAVEQQRRGAGLRRSLRPRSAVATELDLASNDYLGLSQHPDVIDGGVAALRVWGAGATGSRLVTGDTILHHELECELAEFVGACVGLLFSSGYAANLGAVVGLSGPGSLIVSDAYSHASLVDACRLSRARVVVTPHCDVDAVDTALRSCHEERAVVVTESVFSADGVLAPVSELHDVCRRHGALLLVDEAHGLGVRGGGRGLVYEVGLAGAPDVVITTTMSKALGSQGGAVLGSSAVRAHLINTARPFIFDTGLAPAAVGAARAALQILKAETWRPEAVLQHARTLAKICDLSELPQSAVVSVVLGDPEVALAAAIACLDAGVRVGCFRPPTVPAGTSRLRLTAHASLDSAKLEVARRVLTDVLGGCCVARR_L

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding BioF with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

10 show weak predicted evidence for PPIs

View all pooled AlphaFold results for BioF

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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