papA3
mL1230
PROBABLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA3
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1460739 – 1462154
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1230_papA3_dna
CAGGTAGGGCCGTTGACACTGGGGACACTGCTGGATTGGGCACCCCGAGCGGGGAAGACCATCTCGTGGCAACCGACACCTGCTACCTGCGAGAAGGTGTCGCAGGCGCCGGTGAGTTCGGTACCGGTCGCCTACATGCAAGCACAGCACATCCGTGGTTATGTCGAGCAGAAAGCAAAGGGGCTCGACTACTCACGGCTGATGATTGTCAGCTGTGACCAGCTCGGCCAATGTGATATCCGTGCGATCAACTACATCGTCAACGCGCACCTGCGCCGCCATGATACCTACCGTAGCTGGTTTGAGTATACCGACGAAGGCGAAATCATCCGGCACACGTTATGCGATCCCGCAGACATCGAATTCGTGCCCATCGAACATGGCCAGCTGTCGCTGGCACAAATACGTGAACTTGCGGTGAGTACACCAGATCCGCTGGAGTGGGGCTGCTTCCAGTTCGGTGTGATCCAAGCTGAGGAGCATTTCACGTTCTATGCCAGTATCGACCACGTCCATGTGGACGCGATGATCGTTGGCGTGACGCTCATGGAATTCCATATGATGTACAGCGCACTCGTCAGTGGTGCTGGTCCCCTCGAGCTGCCGGAGGCGGGTAGCTACGATGACTTCTGCCGCCGCCAGCACCGATTCACCTCTATGCTCACTGCGGAGTCTCCACAGATTCGCTCGTGGACCCAATTCGCTGAGCCGAACGAAGGCAGTTTTCCCGATTTCCCGCTGCCACTCGGTGATCCATTGGAGCCCACTCAGGCCGACATTGTCACCATAACCATGCTCGATGAGCAGCAGACGGATCGATTCGAAGCGGCATGTACAGTTGCTGGTGCTCGTTTTGTCGGTGGCGTGCTGGCTTGCTGCGGCCTGGCCGAGTACGAATTGACCGGTGCTGACACCTATTATGGGCTCACACCGCGCGACACCCGTCGCATTCCGACTGATGTCTTGACTCAAGGCTGGTTCACCGGACTGGTGCCGATCACGGTCCCTATTGCTGGCTCATCGTTCGGCGATGCCGCGCGCGCCGCGCAGAATTGCTTCGACACCGACGTGCACTTAGCTGAAGTTCCCTACGACCGGGTGGTGGAATTGGCACCGACAGTGCATAAGCCGCGGCCGAACTTCCCAGTGATCAACTTTCTTGATGCGGGAACCGCGCCGCTTTCGGTATTGCTTACCGCGGGATTGGACGGCCTCAATATCGGCGTCTATAGCGATGGTCGTTACTCGTATCAGATGTCGATCTACGTGATCCGGGTTGAGCAGGAGACTGCGGTGGCGGTGATGTTTCCGGATAATCCGGAAGCCCAGGAGTCGGTCGCCCGCTATCTGGAGACGTTGAAGTCCGTGTTCGAGTGCGTCGCCGAAAGTGGGCACTGGCGTAATGTCGCATGATAT

Protein Sequence 

>ML1230_PapA3_protein
QVGPLTLGTLLDWAPRAGKTISWQPTPATCEKVSQAPVSSVPVAYMQAQHIRGYVEQKAKGLDYSRLMIVSCDQLGQCDIRAINYIVNAHLRRHDTYRSWFEYTDEGEIIRHTLCDPADIEFVPIEHGQLSLAQIRELAVSTPDPLEWGCFQFGVIQAEEHFTFYASIDHVHVDAMIVGVTLMEFHMMYSALVSGAGPLELPEAGSYDDFCRRQHRFTSMLTAESPQIRSWTQFAEPNEGSFPDFPLPLGDPLEPTQADIVTITMLDEQQTDRFEAACTVAGARFVGGVLACCGLAEYELTGADTYYGLTPRDTRRIPTDVLTQGWFTGLVPITVPIAGSSFGDAARAAQNCFDTDVHLAEVPYDRVVELAPTVHKPRPNFPVINFLDAGTAPLSVLLTAGLDGLNIGVYSDGRYSYQMSIYVIRVEQETAVAVMFPDNPEAQESVARYLETLKSVFECVAESGHWRNVA_Y

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PapA3 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

30 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PapA3

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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