mmpL10
mL1231
PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL10
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1462236 – 1465187
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1231_mmpL10_dna
GTAATCGGTTGCTGGACTCTACTTGCGCTGATGCTCCCGATGACGGTGCCGTCGTTGACGGAGCTAACTCAGCGTCATCCCGTCGTGATTCTGCCTGTTGATGCGCCGTCGAGCGTCGCAGCCAAAAAGATCTCCCAGGCATTTCACGAGGTGGATTCGGAAAACGTATTGATCGTGCTGCTGACCGACGACAAGGGGTTAGGACCGGCCGACGAAACCGTTTACCGCACGCTGGTGGATCGGCTGCGCAATGATACCAAAGACGTTGTGGTGTTACAGGATTTCCTCAGCACACCGCCGTTGCATGAGTTACTGGTTAGCAAAGACGGCAAGGCGTGGATCCTGCCGATCGTCCTGGCCGGTGAGCTTGGCACGTCCGCGTCCTATCAGGCCTACGCAGGCGTCGCGGGCATCGTGAAACAAACCTTGGAAAGCACAGCCGGATCGTCTCTCAAGGCCAACTTAACGGGGCCGGCGTCCACCGTCGCTGACTTGACGGACGCCGGGGCACGAGATCGCACGTCGATCGAGCTGGTGATCGCCGTTTTGTTGCTAACTATTTTGATGATTATCTATCGCAACCCGATCACCATGTTGTTGCCGTTGATCACGATCGGTGCATCGTTGATGACTGCGCAGGCCGTGGTATCTGGCGTCTCAGTACTGGCCGGTCTGGCTGTTTCCAACCAGATGATCGTGTTGCTCAGTGCGATGATCGCCGGTGCGGGAACTGATTATGCGGTGTTCCTCATCAGCAGGTATCACGACTACATTAGGATGGGGTCTGGTTCGGCGCAGGATGCGGGTTGCGCCGTGCGACAAGCACTGATTTCCCTAGGCAAGGTGATCGCCGCGTCGGCGGCAACAGTAGGTATCACTTTCCTAGGGATGAGCTTTACCAAAATCAGAGTGTTTTCCACGGTCGGTCCGGCACTGGCGATTGGGATCGCGGTAGCGTTCTTGGCTGCGGTGACCTTGATGCCGGCCCTCCTGGTGCTCGCCGGGACGCGTGGTTGGGTCGCGCCGCGGCGTGACCGCGCCGGCGCATTCTGGCGGCGAACCGGGGTGCGGATAGTGCGCCGGCCAGTGGCTTACTTGAGTGCGAGCATGGTCATTCTGATTGTGTTGGCCCTGTGCGCCAGCCTCGTTCGATTCAACTACGATGACCGCAAGCAGATACCGGCCTCTGATGAGAGCTCTGTCGGATATGCTGCCCTGGAAAGCCATTTCCCAGTAGGTCAAGCGATTCCGGAGTACCTGCTGATCCAATCGCCGCACGACCTGCGCACGCCTCGTGCCCTTGCCGATATGGCTGAGCTGGCGCAACGAGTGAGCCAGATTCCGGGCATTGCTCTGGTCCGTGGGGTTACTCGACCCACTGGAAAGCCGCTTGAAGAGACTAGTGCGACGTATCAGGCGGGCATGGTTGGTAAACAGCTAGGCAGTGCATCTCATCTCATCGGTGAAAGCACCGGCGACTTGAACCGACTGGCCTCGGGTGCTGGTCTGTTGGCAGACAAGCTTGGTGACGTACGCATTCAAGTTGGCCAGGCCGTCGCAGGGATCAGTGGGTTGCTCGACAATTTGGCGTTCGCGCAGAAGATGTTTGGTGACAGCAAGACGTTGGGCGAAATCGACACTGCCGGCAAGCTTGTCTCGAGTATGCGTGCTCTCGGCAACATGTTTGGGATTAATTTCTCAACCACGATGAACGACATCAACTGGGTTGGCGCCGTGGTCATTGCTCTGGATTCCAGTGTGCTTTGCGACACTAATCCCATCTGCGCCGATGCGCGCGCTCAGTTCCACAAGCTGCTCACCGCATCTGAAGACGGAACTCTGGACAATATCGCCCACCTCTGGAAGCAGTTGGGGTCGACGCAGTCCTCGCAGACCATAGGCGCCACGGTCAGTGGTCTGGAGAAAACACTGACCGCCGTTAATACGTCGCTGCGCTCCTTGGGGCTGGATAATCCGAATGTTATGCGCTCAAAGATGATCGGTTTGCAAAACGGTGTCAACGACCTTGCGAGCGCCGGACGTCGGATCGCCGACGGTGTGGCGGTGCTCGTTGATCAGACCAGGACTATGGGCACCAGTCTTGCCCGGGCATCGGCCTTTTTGATGGAGATGGGTCAAGACGCATCTCAACCGTCCATGGCCGGATTCAATGTGCCGCCGCAATTGCTCAATACGGAAGATTTTAAGAAACTCGTCCAGGCATTCATCTCGCCAGACGGCCATTCGGTGCGGTACTTCATTCAAACCGATCTCAACCCGTTCAGCAGTGCGGCCATGGATCAGGTCAACACGATCCTCAACGTCGCCACAGGTGCTCAGCCAAACACCACATTGTCGGACGCGTCGATCTACCTTTCGGGCTATACCGTGACGCTTCGAGACACCAGAGACTACTACGACCGAGATCTGCAGCTTATAGTCATCGTCACGATGATTGTGGTGCTTTTGATCCTTATGGCACTATTGCGCTCGATAGTTGCGCCAATATACCTCGTCGGGTCGGTGATTGTTTCGTATCTGTCGGCACTCGGACTCTGTGTCTTGGTGTTCCAGGTGCTATTGCGGCAGCAATTGCATTGGAGCGTGCCGGGATTGGCGTTCGTGGTGCTGGTCGCCGTGGGTGCTGACTACAACATGTTGCTCGCATCACGGCTGCGTGACGAGTCGTCACATGGCTTGCGTGCAAGCGTTATTCGCACCGTACGTTCCACCGGTGGAGTCATAACCGCGGCGGGTTTAATCTTCGCTGCATCGATGTTTGGTCTGCTGTTGTCCAGCATCGCGACTGTCGTGCAGGCAGGCTTCGTGCTTGGGTCCGGGATCTTGCTCGACACTTTCATTGTCCGTACTATTACCGTGCCTGCGGTCGCTGCTTTGTTGAGACGGGCGAGTTGGTGGCCCGCACGGCCGTGGGGTAACAACGCGTAGTCG

Protein Sequence 

>ML1231_MmpL10_protein
VIGCWTLLALMLPMTVPSLTELTQRHPVVILPVDAPSSVAAKKISQAFHEVDSENVLIVLLTDDKGLGPADETVYRTLVDRLRNDTKDVVVLQDFLSTPPLHELLVSKDGKAWILPIVLAGELGTSASYQAYAGVAGIVKQTLESTAGSSLKANLTGPASTVADLTDAGARDRTSIELVIAVLLLTILMIIYRNPITMLLPLITIGASLMTAQAVVSGVSVLAGLAVSNQMIVLLSAMIAGAGTDYAVFLISRYHDYIRMGSGSAQDAGCAVRQALISLGKVIAASAATVGITFLGMSFTKIRVFSTVGPALAIGIAVAFLAAVTLMPALLVLAGTRGWVAPRRDRAGAFWRRTGVRIVRRPVAYLSASMVILIVLALCASLVRFNYDDRKQIPASDESSVGYAALESHFPVGQAIPEYLLIQSPHDLRTPRALADMAELAQRVSQIPGIALVRGVTRPTGKPLEETSATYQAGMVGKQLGSASHLIGESTGDLNRLASGAGLLADKLGDVRIQVGQAVAGISGLLDNLAFAQKMFGDSKTLGEIDTAGKLVSSMRALGNMFGINFSTTMNDINWVGAVVIALDSSVLCDTNPICADARAQFHKLLTASEDGTLDNIAHLWKQLGSTQSSQTIGATVSGLEKTLTAVNTSLRSLGLDNPNVMRSKMIGLQNGVNDLASAGRRIADGVAVLVDQTRTMGTSLARASAFLMEMGQDASQPSMAGFNVPPQLLNTEDFKKLVQAFISPDGHSVRYFIQTDLNPFSSAAMDQVNTILNVATGAQPNTTLSDASIYLSGYTVTLRDTRDYYDRDLQLIVIVTMIVVLLILMALLRSIVAPIYLVGSVIVSYLSALGLCVLVFQVLLRQQLHWSVPGLAFVVLVAVGADYNMLLASRLRDESSHGLRASVIRTVRSTGGVITAAGLIFAASMFGLLLSSIATVVQAGFVLGSGILLDTFIVRTITVPAVAALLRRASWWPARPWGNNA_S

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding MmpL10 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

10 show intermediate predicted evidence for PPIs

76 show weak predicted evidence for PPIs

View all pooled AlphaFold results for MmpL10

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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