fadD21
mL1234c
PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1467578 – 1469317
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1234c_fadD21_dna
CCCATGCAAAACTCGTCCGTCCTTTCTTTCCTGCGCGAACGTGCCGGCCTGCAGCCAGACGATGAAGCATTCAGCTTCACCGACTACGAGCAGGATTGGGCGGGTGTCCGCAAAACACTGACTTGGGCGCAGCTGTATCAACGAACCTTGAACGTTGCGCACGAGCTCAGGCGGCACGGTTCGATAAGAGACCGGGCAGTGATATTGGCTCCCCAGGGGCTGGACTATATCATCGCGTTCCTGGGAGCTATGCAGGCTGGCTTTATCGCCGTTCCGCTGTCAGTACCTCAGGCCGGCTCCCATGACGAACGTGTCGGAGCTGTGCTTGCCGACACATCACCCTCGGTCGTCCTGACAACGTCTGCGGTTGCCGATGCGATCGCGAAATACGTTGACCACTCTGACACCGACACCGTCCCGGCGATCCTCGAAGTCGACTCACCAAATCTAGACGTCGAGAATAAATCGAATATTAGACTCACCGATGCGCCGAGCACAGCGTACTTACAGTACACCTCGGGTTCGACCCGCCTTCCAGCCGGGGTCATGGTCACGCACCGGAACCTTATGGTGAATTTCCAACAGTTGATGGCTGACTACTTCGCTCCCACTAACGGTGTGGCGCCACTCGATCTCACCATCGTGTCGTGGCTGCCGTTCTACCACGATATGGGCTTGGTTCTCGGCGTCGTCGCACCAATTCTGGGCGGCTGGCGGAGCGAGCTTACGAGTCCGATCTCGTTTTTGCAACGTCCAGCCAGGTGGATCCAAGCGATGGCCACCAGCAGCCACCCATTTTCTGCAGGACCGAACTTCGCCTTCGAATTGGCTGCACGCCGGACATCAGACGCAGATATAGCCGGCCTCGATCTCGGCGCTTGCCAGGGCATCATCAGCGGCAGTGAACGAATCCACCCCGCCACGCTAAATCGGTTCTCGGATCGGTTTGCCCGAATCAATTTCCGCGACGACATGATGCTACCCTCCTACGGGTTAGCTGAAGGAACTGTCTATGCCGCCAGCCGCCCTAAGGGAAGCTCGCCAGAGGTCGTTTATTTCGAACCCGCGAAGCTGTCGGAAGGCACCGTGAAACGGTGCGAAGCACGGACCGGCGCGCCACTGCTGAGCTACGGCACGCCGAAGTCACCAATAGTGCGAATCGTGGATTCCGACACGTGCATCGAGTGCCCAACAGGAAGGGTAGGCGAAATCTGGCTACATGGTGACAACGTCGCCGAAGGCTATTGGCACAAACCGGAGGAAACGCAACGTACCTTCGGCGGAAAGCTAGCTAACCCCTCGCCAGGCACACCCGAGGGACCGTGGTTGAGAACCGGAGACCTCGGGTTTATCTCCGAGGATGAGCTGTTCATCGTGGGCCGTATGAAAGATCTGCTGATCGTGTATGGACGCAACCACTACCCTGAAGACATCGAATCGACGGTCCAGGAAATCACCGGTGGTCGGGTCGCGGCGATATCCGTCCCGGTTGATGAGACCGAAAAATTGGTCACCATTATCGAAGTCAAAAAGCGCGGCGACTCCGACGCGGAAGCGATGCAGAAGCTCGTCGCCGTCAAAAACAACATCACCGCGGCTATATCCAAGTCACATGGTCTGAACGTAGCCGACCTCGTTCTGGTACCGCCGGGGTCAATTCCTACCACGACCAGCGGCAAGGTTAGGCGGACCGCCTGTGTCGAGCAGTATAGGCGGCAGCAGTTCTCCCGGTTAGACGGC

Protein Sequence 

>ML1234c_FadD21_protein
PMQNSSVLSFLRERAGLQPDDEAFSFTDYEQDWAGVRKTLTWAQLYQRTLNVAHELRRHGSIRDRAVILAPQGLDYIIAFLGAMQAGFIAVPLSVPQAGSHDERVGAVLADTSPSVVLTTSAVADAIAKYVDHSDTDTVPAILEVDSPNLDVENKSNIRLTDAPSTAYLQYTSGSTRLPAGVMVTHRNLMVNFQQLMADYFAPTNGVAPLDLTIVSWLPFYHDMGLVLGVVAPILGGWRSELTSPISFLQRPARWIQAMATSSHPFSAGPNFAFELAARRTSDADIAGLDLGACQGIISGSERIHPATLNRFSDRFARINFRDDMMLPSYGLAEGTVYAASRPKGSSPEVVYFEPAKLSEGTVKRCEARTGAPLLSYGTPKSPIVRIVDSDTCIECPTGRVGEIWLHGDNVAEGYWHKPEETQRTFGGKLANPSPGTPEGPWLRTGDLGFISEDELFIVGRMKDLLIVYGRNHYPEDIESTVQEITGGRVAAISVPVDETEKLVTIIEVKKRGDSDAEAMQKLVAVKNNITAAISKSHGLNVADLVLVPPGSIPTTTSGKVRRTACVEQYRRQQFSRLDG

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding FadD21 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

37 show weak predicted evidence for PPIs

View all pooled AlphaFold results for FadD21

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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