trpC
mL1271
Probable indole-3-glycerol phosphate synthase TrpC
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1514503 – 1515321
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1271_trpC_dna
TGTCCGGCAACTGTGCTTGACTCCATTCTAAAGGGAGTCCGGGCCGACGTTGCCGCACGCGAAGCCTGCATCAGCCTGTCCGAAATCAAAGCCGCCGCCGCGGCCGCACCAGCACCGCTGGACGCTATGGCCGCTTTACGTGAGCCCGGTATTGGTGTTATCGCCGAGGTCAAGCGCGCCAGTCCATCGGTGGGCTCATTGGCCACCATCGCTGATCCGGCAAAGCTGGCCCAGGCCTACGAGGACGGCGGTGCTCGGATCATCAGCGTTTTGACCGAGGAACGTCGCTTTAACGGTTCACTCGACGATCTCGATGCAGTGCGCGCCGCGGTTTCAGTACCGGTGTTGCGCAAAGACTTTGTGGTGCAGCCATATCAGATCCATGAGGCGCGCGCGCACGGTGCCGATATGTTGTTGTTGATCGTTGCTGCGTTGGACCAATCGGCGTTGATGTCTATGCTGGACCGCACCGAATCACTTGGTATGATTGCTCTCGTTGAAGTCCGCACGGAACAGGAAGCGGACCGGGCCCTAAAGGCAGGGGCCAAGGTGATAGGTGTAAACGCTCGCGATTTAATGACGTTGGAAGTGGACCGGGATTGCTTCTCGCGAATTGCTCCTGGGTTGCCGAGTAACGTGATCAGGATCGCCGAATCCGGTGTACGTGGCCCCGCGGATCTGTTGGCTTACGCTGGTGCGGGAGCGGACGCCGTGTTGGTCGGCGAAGGCCTGGTGAAAAGTGGTGACCCGCGGGCAGCGGTTGCCGATCTGGTCACCGCGGGTACCCACCCGTCATGCCCAAAACCGGCTCGCTAGTCA

Protein Sequence 

>ML1271_TrpC_protein
CPATVLDSILKGVRADVAAREACISLSEIKAAAAAAPAPLDAMAALREPGIGVIAEVKRASPSVGSLATIADPAKLAQAYEDGGARIISVLTEERRFNGSLDDLDAVRAAVSVPVLRKDFVVQPYQIHEARAHGADMLLLIVAALDQSALMSMLDRTESLGMIALVEVRTEQEADRALKAGAKVIGVNARDLMTLEVDRDCFSRIAPGLPSNVIRIAESGVRGPADLLAYAGAGADAVLVGEGLVKSGDPRAAVADLVTAGTHPSCPKPAR_S

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding TrpC with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

30 show weak predicted evidence for PPIs

View all pooled AlphaFold results for TrpC

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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