ML1286
mL1286
Probable two-component system transcriptional regulator
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1531870 – 1532487
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1286_ML1286_dna
ACCGGACCCACGACCGACGCCGACGCCGCCACGCCGCACCGGGTTCTGATTGCTGAAGACGAAGCACTCATACGACTCGACCTGGCCGAGATGCTGCGAGATGAGGGGTACGACATCGTTGGAGAAGCCGCTGATGGCCAGGAAGCGGTCGAACTGGCAGAACGCCATAAACCCGACCTGGTGATCATGGATGTGAAGATGCCGCGCCGTGATGGGATCGACGCAGCATCGGAGATAGCCAGCAAACGCATCGCGCCGATCGTGGTGCTGACTGCGTTCAGTCAGCGCGACTTGGTTGAACGCGCACGCGATGCGGGGGCTATGGCCTACTTGGTTAAGCCTTTCACCATCAGCGATTTGATTCCGGCCATAGCATTGGCGATGAGCCGGTTTAGTGAGCTCACCGCGCTGGAACGCGAAGTCGCGACGCTGGCTGACCGGCTGGAGACCCGTAAGCTTGTTGAGCGAGCCAAAGGCCTACTGCAGGTCAAACAGGGCATGACTGAGCCCGAGGCGTTCAAATGGATTCAACGTGCCGCCATGGATCGGCGGACCACGATGAAACGGGTGGCTGAAGTTGTCCTGGAAACCCTTGACACTCCCAAAGACACCTAGGGC

Protein Sequence 

>ML1286_ML1286_protein
TGPTTDADAATPHRVLIAEDEALIRLDLAEMLRDEGYDIVGEAADGQEAVELAERHKPDLVIMDVKMPRRDGIDAASEIASKRIAPIVVLTAFSQRDLVERARDAGAMAYLVKPFTISDLIPAIALAMSRFSELTALEREVATLADRLETRKLVERAKGLLQVKQGMTEPEAFKWIQRAAMDRRTTMKRVAEVVLETLDTPKDT_G

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML1286 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

16 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML1286

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.