lppK
mL1315c
Probable conserved lipoprotein LppK
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1567376 – 1567960
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1315c_lppK_dna
GAACGTGTCGCGCTGGACGCATCGAACCTTTTTCATCGCCCTGAGCGCTATCGTAACCACGGCAGGATTTGGGTCCTCGGGATGTGCACATGGCAACTCCAGCACATCAGAGTCGGCTGTCCCATCCACTTTCCCAGGCATTTCGAGTTCAATTACTGCTCCGCCAGCTACTGGCCTGCCGGCTCCGGAAGTCCTTACCAATGTGCTTAGCCGGCTCGCCGACCCCAACATTCCGGGCATCGACAAGTTACCCCTCATCGAAAGCGCAACCCCTGACAGCGCTGTCACCCTGGACAAATTCAGCAACGCATTACGGGACAACGGCTACCTGCCGATGACCTTCACGGCGAACAACATCGCATGGTCAAACAAGAATCCGTCCGATGTGCTAGCCACTATCAGTGTCAACATCGCCCAAACGAACAACAGCGTATTCTCGTTCCCGATGGAGTTCACACCCTTCCCGCCCCCGCAACAGAGCTGGCAGTTATCCAAGCGAACCGCAGACATGCTGCTAGAGTTCGGAAATTCATCGGGCCTAACTAACCCAGCACCAATCAAGGCGCCGACCCCAACACCTTCGCA

Protein Sequence 

>ML1315c_LppK_protein
ERVALDASNLFHRPERYRNHGRIWVLGMCTWQLQHIRVGCPIHFPRHFEFNYCSASYWPAGSGSPYQCA_PARRPQHSGHRQVTPHRKRNP_QRCHPGQIQQRITGQRLPADDLHGEQHRMVKQESVRCASHYQCQHRPNEQQRILVPDGVHTLPAPATELAVIQANRRHAARVRKFIGPN_PSTNQGADPNTFA

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding LppK with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

16 show weak predicted evidence for PPIs

View all pooled AlphaFold results for LppK

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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