mpa
mL1316
Probable mycobacterium proteasome ATPase Mpa
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1568248 – 1570077
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1316_mpa_dna
GTGAGTCAGAGCGTTCTGAAGCATTCAATCCCCCTCGTGAAGCGGGCATGTCCAGCGGCGATATTGCTGAATTGGAACAACTACGACGCGAGATAGTGGTGTTGCGTGAGCAACTTGAGCATGCGGTTGGACCGCATGGGAGTGTCCGCTCTGTGCGCGATGTGCATCAGCTCGAAGCTCGAATTGACTCGCTTACGGCCCGCAATTCTAAATTAATGGACACTCTTAAAGAAGCCCGTCAACAACTGTTGGCGCTGCGTGAGGAAGTCGACCGGCTAGGACAGCCGCCCAGCGGGTACGGCGTGCTATTGGCCGCTCACGATGACGAAACGGTCGATGTGTTCACGTCGGGCCGCAAGATGCGGCTCACGTGCTCACCTAATATCGAGGTTGCGTCGTTACGGAAGGGCCAGACCGTCCGGCTCAACGAGGCCCTGACCGTCGTCGAAGCTGGTACCTTCGAGGCGGTCGGTGAGGTATCCACCTTGCGGGAGGTCTTGGCGGACGGTCACCGCGCGCTGGTCGTCGGCCACGCTGACGAGGAACGCATCGTTTGTTTAGCTGAGCCGCTGGTTGCCGAGAATTTGCTGGACGGCGTTCCCGGTGCCCTCAACGATGATAGCCGGCCGCGCAAACTGCGTCCTGGAGACTCGCTGTTGGTCGACCCCAAGGCCGGCTATGCTTTCGAACGTGTCCCCAAGGCCGAGGTTGAAGACCTGGTGCTGGAAGAGGTGCCCGATGTTAGCTACCAGGACATCGGCGGTCTGACCCGCCAGATCGAACAGATCCGCGATGCCGTGGAGCTGCCGTTCCTGCACAAGGAGTTGTACCGGGAGTACGCACTGCGCCCACCCAAAGGGGTGTTACTTTATGGTCCGCCCGGCTGTGGCAAGACACTGATCGCCAAGGCGGTGGCCAACTCTCTGGCTAAGAAGATGGCTGAGGTTCGCGGCGACGACGCCCGCGAGGCTAAATCGTACTTCCTCAACATCAAAGGTCCCGAACTATTGAACAAGTTCGTCGGCGAGACTGAACGACACATCCGGCTGATCTTCCAGCGCGCGAGAGAGAAGGCGTCGGAAGGAACACCGGTGATCGTGTTCTTCGACGAGATGGACTCGATTTTCCGTACCCGCGGCACCGGTGTCTCCTCGGATGTCGAGACAACCGTGGTGCCGCAGCTGCTCAGCGAGATCGACGGGGTAGAAGGCCTCGAGAACGTCATCGTGATCGGCGCCTCCAACCGCGAAGACATGATCGACCCCGCGATTCTGCGGCCCGGGCGTCTCGACGTGAAGATCAAGATCGAACGGCCCGATGCCGAAGCGGCGCAAGACATCTACTCGAAGTACCTGACCGAGTCGCTGCCGGTGCATGCCGACGACCTCACCGAGTTCGATGGTGACCGTGCGGCTTGCATAAAGGCCATGATCGAAAAGGTTGTCGACCGGATGTATGCCGAGATCGACGACAACCGTTTCCTGGAAGTCACTTATGCCAACGGGGACAAGGAAGTCATGTACTTTAAGGACTTCAACTCCGGGGCGATGATCCAAAACGTCGTAGATCGGGCGAAGAAGAACGCCATCAAGTCAGTGCTGGAGACCGGTCAACCCGGGTTGCGAATTCAACATCTGCTCGACTCGATCGTTGACGAGTTCGCTGAAAACGAGGATCTTCCCAACACCACCAATCCTGATGACTGGGCGCGGATTTCGGGCAAGAAGGGTGAGCGGATCGTCTACATTCGCACTTTGGTTACTGGTAAGAGTTCGAGTGCCAGCCGGGCAATTGATACTGAATCCAACCTCGGCCAGTACCTGTAGGCAT

Protein Sequence 

>ML1316_Mpa_protein
VSQSVLKHSIPLVKRACPAAILLNWNNYDAR_WCCVSNLSMRLDRMGVSALCAMCISSKLELTRLRPAILN_WTLLKKPVNNCWRCVRKSTG_DSRPAGTACYWPLTMTKRSMCSRRAARCGSRAHLISRLRRYGRARPSGSTRP_PSSKLVPSRRSVRYPPCGRSWRTVTARWSSATLTRNASFV_LSRWLPRICWTAFPVPSTMIAGRANCVLETRCWSTPRPAMLSNVSPRPRLKTWCWKRCPMLATRTSAV_PARSNRSAMPWSCRSCTRSCTGSTHCAHPKGCYFMVRPAVARH_SPRRWPTLWLRRWLRFAATTPARLNRTSSTSKVPNY_TSSSARLNDTSG_SSSARERRRRKEHR_SCSSTRWTRFSVPAAPVSPRMSRQPWCRSCSARSTG_KASRTSS_SAPPTAKT_STPRFCGPGVST_RSRSNGPMPKRRKTSTRST_PSRCRCMPTTSPSSMVTVRLA_RP_SKRLSTGCMPRSTTTVSWKSLMPTGTRKSCTLRTSTPGR_SKTS_IGRRRTPSSQCWRPVNPGCEFNICSTRSLTSSLKTRIFPTPPILMTGRGFRARRVSGSSTFALWLLVRVRVPAGQLILNPTSASTCRH

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Mpa with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

15 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Mpa

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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