dop
mL1320
conserved hypothetical protein
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1573921 – 1575465
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1320_dop_dna
AGCGGATTATTGGGACGGAGGTAGAGTATGGCATTTCGTCCCCGTCGGACCCGACCGCCAACCCGATCCTCACCTCGACGCAGGCGGTCTTGGCCTACGCTGCTGCCGCTGGCATTCAGCGTGTTAAACGCACCCGCTGGGACTACGAGGTGGAATCGCCGCTGCGGGACGCCCGGGGCTTCGATCTAAGCCGGTCAGCGGGACCGCCGCCGGTGGTGGACGCCGATGAAGTTGGCGCTGCCAACATGATCTTGACCAACGGGGCGCGGCTGTATGTCGATCATGCGCACCCGGAGTACTCTGCCCCCGAATGCACCGACCCGCTGGACGCAGTGATCTGGGACAAGGCTGGGGAGCGTGTGATGGAAGCCGCCGCTCGGCATGTCGCTAGTGTGCCGGGAGCCGCCAAACTGCAGTTGTACAAGAACAATGTTGACGGCAAGGGTGCCTCCTATGGGGCGCATGAGAACTATCTGATGTCGCGGCAGACACCGTTTTCAGCTATCATAGCTGGGTTGACCCCGTTTTTGGTGTCGAGGCAGGTGGTCACCGGCTCTGGGCGGGTCGGCATCGGGCCCGCGGGTGACGAGCCCGGCTTCCAGCTGTCCCAGCGTTCCGATTACATCGAGGTCGAGGTCGGGCTCGAGACTACGCTGAAACGCGGCATTATCAACACTCGCGATGAACCGCACGCCGACGCCGACCGGTATCGCCGGTTGCATGTCATCGTCGGTGATGCCAACCTGGCCGAGACATCGACCTACCTGAAACTGGGCACCACGGCGCTGGTGCTCGATTTGATCGAAGAAGGTCCAGTACACGGAATAGACTTGACCGACCTCACGCTGGCCCGGCCGGTGCATGCTGTCCATGCGATAAGCCGCGATGCATCGTTGCGGGCCACTGTGACGTTGGTCGACGGCCGTGAATTGACCGGTCTTGCGCTACAACGGATTTACCTCGACCGAGTGGCAAAGCTGGTCGACAGCCGTGACCCTGACCCCCGCGCAGCCGACGTCGTGAAAACTTGGGTGCACGTGCTTGACCAGCTGGAGCGCGACCCGATGGACTGTGCTGAACTGCTGGACTGGCCGGCGAAGCTGCGGCTGCTTGAAGGTTTTCGGCAGCGGGAGAACTTGAACTGGTCAGCCCCGCGGCTACATCTAGTCGACCTGCAGTATTCTGACGTTCGGTTGGACAAGGGGCTGTATAATAGGTTGGTCGCCCGCGGCTCGATGAAACGTCTGGTCAACGAACACCAGGTGCTCCGGGCGGTGAACAACCCGCCGACCGATACTCGCGCGTATTTTCGCGGCGAATGCTTGCGCCGGTTCAGTGCCGACATCGCCGCGGCCAGTTGGGACTCAGTGATCTTTGACCTAGGCGGTGACTCGCTGGTTCGGATCCCGACCTTGGAGCCACTGCGCGGCAGCAAGGCCCATGTCGGAGCGCTGTTGGACTCGGTGGACAGCGCTGCGGAATTAGTGGAGCAATTAACTACTAAGCCTGTTGACCCGGGAAAGGTCGGACTGGACCGGTAGGGTA

Protein Sequence 

>ML1320_Dop_protein
SGLLGRR_SMAFRPRRTRPPTRSSPRRRRSWPTLLPLAFSVLNAPAGTTRWNRRCGTPGASI_AGQRDRRRWWTPMKLALPT_S_PTGRGCMSIMRTRSTLPPNAPTRWTQ_SGTRLGSV_WKPPLGMSLVCREPPNCSCTRTMLTARVPPMGRMRTI_CRGRHRFQLS_LG_PRFWCRGRWSPALGGSASGPRVTSPASSCPSVPITSRSRSGSRLR_NAALSTLAMNRTPTPTGIAGCMSSSVMPTWPRHRPT_NWAPRRWCSI_SKKVQYTE_T_PTSRWPGRCMLSMR_AAMHRCGPL_RWSTAVN_PVLRYNGFTSTEWQSWSTAVTLTPAQPTS_KLGCTCLTSWSATRWTVLNCWTGRRSCGCLKVFGSGRT_TGQPRGYI_STCSILTFGWTRGCIIGWSPAAR_NVWSTNTRCSGR_TTRRPILARIFAANACAGSVPTSPRPVGTQ_SLT_AVTRWFGSRPWSHCAAARPMSERCWTRWTALRN_WSN_LLSLLTRERSDWTGRV

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Dop with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

4 show intermediate predicted evidence for PPIs

34 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Dop

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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