pafB
mL1329
conserved hypothetical protein
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1581170 – 1582165
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1329_pafB_dna
CGACGTCGAAAGTTGAACGGCTGGTCAACCTGGTTATCGCCTTGCTGTCGACCCGTGGCTACATGACCGCTGAAAAGATCAGATCCAGCGTGGCGGGTTACTCCGACAGTCCTACCGTAGAGGCGTTCTCTCGGATGTTTGAGCGCGATAAGAACGAGTTACGTGACCTTGGCATACCGCTCGAGGTCGGCAAGGTGTCGGCGCTAGACCCCTCCGAGGGCTACCGCATCAACCGCGATGCGTACGCACTTCCTCCCGTCGAGCTAACCCCGGACGAAGCGGCTGCAGTAGCTGTCGCAACTCAGCTGTGGGAATCGCAAGAACTGATCACCGCGACACAAGGCGCATTGCTCAAGCTGCGGGCCGCCGGGGTTGACATCGACCCCCTCGATACACCGGTGGTCATCGCCTCATCGTCTGGGGTGTCAAGTCTGCGTGGGTCGGAGGATTTTCTATCAATCCTGTTGTCGGCCATTGGTTCTCGGCAGGCAGTGCAGTTTCCGTACCGGCCGTCACGGGCTGAGCCTTACACCATGCGCAACGTCGAACCGTGGGGTGTGATCACCGAGAACAGTTGCTGGTATCTCGTTGGCCACGACTGCGATCGCAACGCCACCCGCACTTTCCGGCTCTCTCGGATCGGTTCGGAGGTCGCGCCGATCGGGCCTGCCGGCGCTGTCACCGTGCCTGACGGCGTCGATTTGCGCAGAATCGTGTCTGACGCCGTCGCCGAAGTGTCGACCGGCGCTACCGCCCGGGTGTGGGTCGTCGACGGACGGGCCACTGCGTTGCGGCACGCCGGACGACCCGCCGGTGTTCGGCGACTGGGCGGCCGCGACGGTCAGGTGATCGAACTCGACATTGGATCCATCGACCGGCTGGCCCGTGACATCGCTGGCCACGGTGCTGACGCTGTCGTGCTCGAGCCAGACGCTCTGCGCGACGATGTGTTGATACGGTTGCGCGCCCACGCGGGAACAGGGCCTTCATGACACA

Protein Sequence 

>ML1329_PafB_protein
RRRKLNGWSTWLSPCCRPVAT_PLKRSDPAWRVTPTVLP_RRSLGCLSAIRTSYVTLAYRSRSARCRR_TPPRATASTAMRTHFLPSS_PRTKRLQ_LSQLSCGNRKN_SPRHKAHCSSCGPPGLTSTPSIHRWSSPHRLGCQVCVGRRIFYQSCCRPLVLGRQCSFRTGRHGLSLTPCATSNRGV_SPRTVAGISLATTAIATPPALSGSLGSVRRSRRSGLPALSPCLTASICAESCLTPSPKCRPALPPGCGSSTDGPLRCGTPDDPPVFGDWAAATVR_SNSTLDPSTGWPVTSLATVLTLSCSSQTLCATMC_YGCAPTREQGLHDT

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PafB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

36 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PafB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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