pafC
mL1330
Conserved hypothetical protein
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1582162 – 1583136
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1330_pafC_dna
CACAGCTGTCCACCCGCCTAGTGCGGCTGCTCAATATGGTGCCGTACTTCCAGGCTAACCCGCGGATTACCCGTGCGGAAGCTGCCGCCGATCTGGGAGTGTCTGCCAAGCAGCTAGACCAGGACTTCAACCAGCTGTGGGTGTGCGGTCTTCCTGGCTATGGCCCTGGTGATCTCATTGACTTCGAGTTCTCTGGTGACACCATCGAGGTGACCTTCTCAGCGGGCATTGACCGGCCTTTGCAGCTGACGTCGCCGGAGGCCATCGGCCTGTTGGTGGCGCTTCGGGCACTGGCCAACATTCCGGGAGTGGTTGATCCGGAGGCGGTGCGCAGCGCGATCGCCAAGATCGAGGCCGCAGCGGTTGTTATGGGGAACGAGGCCACTGGATCGGTGGCCTCAGTCGATACGCGGCCGTTCTCCGAGAGTCACGCAGTGGCCGCAGTGCGTGCCGCGGTGCGGGACAAACAAGCATTGGTGATCGACTACTACTCTGCGTCACATGACACTTTGACCAGCCGGATTGTCGACCCTATCCGAGTACTCCTGGTGGGTGATCACAGTTACCTTGAGGCTTGGTCGCGCGAAGCCGAAGGGGTTCGGCTGTTCCGCTTCGACCGGATCGTGGTGGCCCGCGAGCTGGATGAGCCGGCCGCTGCACCTGAAACAGTGCGGAAGGCGCTGCCAGACACATCGTTCTTCGATGACGACCCGTTGCTGCCGTCGGCGACGCTGTGGGTAGCGCGTTCGGTGTCCTGGATATTCGAGTACTACCCGATGCGGCAGGCCCATGAGTTGCCGGATGGATCGTTCCAGGCGGTCATGACATACGCTTCGGATGCTTGGATGACGCGCTTGGTGCTAGGATTTGGGTCGGCTGTGCAAGTACAAGCACCGGAGGCGCTCGCGTACCGCGTGCGGAATGCTGCGGTCGCTGCTCTGGAGTCCTACCAGGTTACGGCTCAGGCGTGATGCT

Protein Sequence 

>ML1330_PafC_protein
HSCPPA_CGCSIWCRTSRLTRGLPVRKLPPIWECLPSS_TRTSTSCGCAVFLAMALVISLTSSSLVTPSR_PSQRALTGLCS_RRRRPSACWWRFGHWPTFREWLIRRRCAARSPRSRPQRLLWGTRPLDRWPQSIRGRSPRVTQWPQCVPRCGTNKHW_STTTLRHMTL_PAGLSTLSEYSWWVITVTLRLGRAKPKGFGCSASTGSWWPASWMSRPLHLKQCGRRCQTHRSSMTTRCCRRRRCG_RVRCPGYSSTTRCGRPMSCRMDRSRRS_HTLRMLG_RAWC_DLGRLCKYKHRRRSRTACGMLRSLLWSPTRLRLRRDA

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PafC with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

4 show intermediate predicted evidence for PPIs

42 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PafC

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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