ribD
mL1340c
POSSIBLE BIFUNCTIONAL ENZYME RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBD: DIAMINOHYDROXYPHOSPHORIBOSYLAMINOPYRIMIDINE DEAMINASE (RIBOFLAVIN-SPECIFIC DEAMINASE) + 5-AMINO-6-(5-PHOSPHORIBOSYLAMINO)URACIL REDUCTASE (HTP REDUCTASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1598386 – 1599192
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1340c_ribD_dna
ACGGATGTCCGACTTTGAAACCGGTCCAGCAGCCAGCACCACCGCTGGCCGAGCCGCCCAGACGCCGCTGTTAATGCTCACCTCTGGGCGCTATCTCGACGACGACGAACTCTCCCAGCTCTACGGCTACCCGTCCGAACGCGCCGGCGTCTGGATACGGGCAAACTTCATCACCAGTATAGACGGCGGTGCCACCGCCGACGGCAGGACCGGCGCCATGGCAGGGCCAGGCGACCGATTTGTGTTCAACATGCTGCGCGAACTCGCTGATGTGATCGTCGTCGGCGCGGGCACCGTACGGATCGAGAACTATTCCGGCGCGCACCTGCCGGTAACCAAGCGCCAGCAGCGGCAGGCCCGCGGCCAAAGTGAAGTCCCCCAATTAGCGATTGTCACAAATTCGGGTCGGCTGGATCGGGATATGGCGGTGTTTACCCGGACCGAGATAGCACCACTGGTGCTCACCTGTACGGAGACCGCCAAGAAGCTGCGCACGCGGTTAGCTGATCTTGCCTACGTGGTCAGCTGCTCTGGCGACGATCCCAGCAAGGTCGACGAGACTGTCGTATTGGCGACCCTACAGACTCGCGGTCTGCGCCGGGTCCTTACCGAAGGCGGGCCGATGCTGCTCGGCTCGTTTATCCAGCACGGCATGCTCGACGAGCTGTGTCTGACCATCGCACCTTTGATAGTGGGCGGCCGGGCTCGACGTATCGCGACAGGCCCGGAGCAGCTGCTCACCCGTATGCGCTGTGCCCACGTTCTCACTGACGATGCCGGCTACCTTTACACCCGCTACGTCAAGGC

Protein Sequence 

>ML1340c_RibD_protein
TDVRL_NRSSSQHHRWPSRPDAAVNAHLWALSRRRRTLPALRLPVRTRRRLDTGKLHHQYRRRCHRRRQDRRHGRARRPICVQHAARTR_CDRRRRGHRTDRELFRRAPAGNQAPAAAGPRPK_SPPISDCHKFGSAGSGYGGVYPDRDSTTGAHLYGDRQEAAHAVS_SCLRGQLLWRRSQQGRRDCRIGDPTDSRSAPGPYRRRADAARLVYPARHARRAVSDHRTFDSGRPGSTYRDRPGAAAHPYALCPRSH_RCRLPLHPLRQG

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding RibD with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

15 show weak predicted evidence for PPIs

View all pooled AlphaFold results for RibD

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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