ML1346
mL1346
possible long-chain acyl-CoA synthase
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1606117 – 1609125
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1346_ML1346_dna
ATCTCAATTTTTCAATCGTCACACGACCAGTCGAGCGTCTGGTCGCTACGGCACAAAATGGCCTGGAAGTTTTGCGGTTGGGGGGGTTAGAAACAGGCAGCTTTCCGTCACCGTCGCAGATTGTCGAGAGCGTGCCGATGTACAAGCTTCGACGGTACTTTCCGCCCGGTAACCGGCCTGGGCAACCGCTGTTGGGAGCGCCGGTGCTGATGGTGCACCCGATGATGATGTCGGCGGATATGTGGGACGTCACCCGGGAGGAGGGCGCGGTAGGCATCTTGCACGTCAGGGGGCTTGATCCCTGGGTCATCGACTTCGGCTCACCCGACAAAGTCGAGGGTGGAATGCGTCGGAATCTGGCCGACCACATCGTGGCCCTCAGCGAAGCGGTCGATACTGTCAAGGAAGTCACCGGTAACGATGTGCACCTGGTTGGGTATTCACAGGGTGGCATGTTCTGCTACCAAGCTGCCGCATACCGGCGTTCGGAGAACATCGCTAGCATCGTGGCGTTCGGCTCCCCAGTTGACACTCTAGCCGCGCTTCCCATGGGTATTCCACCAAACTTCGGCGTGGTACTTGCCAATTTTATGGCTGATCACGTCTTCAATCGCTTGGATATCCCAAGCTGGTTGGCGCGTGCCGGTTTTCAGATGTTAGATCCGCTCAAGACGGTCAAAGCCCGGGTCGACTTCGTGCGTCAGCTGCACAATCGTGAAGCTTTGCTGTCGCGTGAACAGCAGCGCCGATTCCTTGAATCCGAAGGGTGGATCGCGTGGTCGGGTCCAGCAATTTCCGAGCTACTTAAGCAGTTCATTGCGCACAATCGAATGATGACGGGCGGTTTTGCTGTCAACGGGCAGATGGTGACGTTAACTGACATCACCTGCCCGGTGCTGGCTTTCGTCGGCGAGGTTGACGACATCGGTCAGCCAGCGTCAGTGCGAGGCATTAGACGCGCAGCACCCAACGCCGAGGTCTACGAGTCTCTGATCCGGACAGGACATTTCGGCCTGGTCGTGGGATCCAGGGCGGCGCAGCAGAGTTGGCCGACCGTCGCCGAATGGGTATGCTGGTTAGCCGCTAATGCTAACAAGCCGGCGAATATCCATATTATGCCGGATCAGCCGGTCGAACACACCGCCAGTGGCGTCGCGATTAGTTCTCGGCTCGCGCACGGACTGGGGGAGGTCTCCGAGACGGCGTTGGCGCTGGCTCGTGGCGTGGCCGATGCGATTGTGGCTGCCAACAGATCCGTTCATACGTTGGCTGTGGAGACAGTCCGGACGTTACCACGTTTGGCTCGGCTCGGACAGCTCAATGACCACACTCGGATCTCGCTAGGCCGTATTATCGGCGAACAAGCTCACGATGCCCCACGGGGTGAGTTCCTGTTGTTCGACGGACGTGTGCATACTTACGAGGCTGTCGACCGGCGAGTCAACAACGTCGTCCGAGGTCTGATCGCGGTCGGGGTGCGGCAGGGTGACCGCGTAGGTGTGCTGATGGAAACTCGTCCCAGCGCACTGGTCGCCATTGCAGCACTGTCTCGGCTGGGTGCGGTTGCCGTGATGATGAGGCCAGATGCCGATCTGGCCGCATCGGTCCGAATCGGGGGAGCGACGAAGATCTTGACTGACCCCGCCAATCTTGGCGTAGTACTTGCTTACGGTCGCCAGTTGACTGGTCAGGTACTGGTGTTGGGTGGCGGTGAGTCACGTGATCTGCACCTGCCGGAGGACGCCTTGCAGCAAAACCAAGTCATCGACATGGAAAAGATCGACCCGAATGCCGTCGACCTGCCGGCCTGGTATCGGCCCAACTCGGGATTGGCTCGGGATCTGGCGTTCATCGCGTGCAGCACGGTCGGCGGCGAGTTGGTAGCTAAGCAGATCACTAACTACCGATGGGCGGTCTCAGCTTTCGGAACTGCCTCAACAGCCGCTCTCGATCGCAGGGACACAGTGTATTGCTTGACGCCGCTGCATCACGAGTCCGCGCTGCTGGTAAGCCTGGGCGGTGCGGTCGTTGGTGGTGCTCGCATAGCGCTGTCGCGCGGTTTATGCTCGAACCGATTTGTGCACGAGGTGCGTCAATACGGCGTCACTGTTGTATCCTACACCTGGGCTATGCTGCGCGAACTTGTCGATGACCCGGCGTTTGTACTGCACGGCAACCATCCGGTGCGGCTGTTCATGGGCTCAGGCATGCCGACCGGCCTATGGGAGCGGGTCGTCGAAGCGTTCGCGCCCGCTCATGTTGTCGAATTTTTCGCTACGGTCGACGGACAAGCTGTACTGGCTAACGTGTCGGGTGCGAAGATTGGTAGCAAGGGTCGTCCGCTGCCCGGCGCTGGGCATGTCGAGTTGGGTGCTTACGACGCCGAACAGGACTTGATCCTGGAAAACGACCGCGGTTTCGTACAGGTCGCCGACGTCAACCAGATTGGTGTGCTACTCGCTGCGTCCCGCGGGCCGATCGATCCGACTGCGTCTGTCAAACGCGGTGTTTTTGCTCCGGCTGACACCTGGATAGCAACCGAGTACTTGTTACGCCGCGACTACGATGGAGACTATTGGCTGGCGGGGCGGCGTAGCTCGGTGGTTCGCACCGCACGCGGATTGGTTTATACTGAACCAGTGACCGACGCGCTCGGCTTCATCACTGGGGTCGACCTCGCTGCGACCTACAGTGTGGCGGTGGATGATCGTGAGTTGGCGGTGTCGGCGGTGACACTGTTGCCCGGAGCGGCCATAACGGCGGCCGACTTGACCGAAGCCGTTGCCAGCATGCCCGTCGGACTGGGGCCCGACATTGTGCACGTGGTACCAGAGCTAACGCTCAGCGCCACCTATCGTCCAATCGTCGGTGCCCTGCGCACGGCCGGGATTCCTAAAACGGGGCGCCAGGTATGGTATTTCGATTCCGCAAGTAATCAATTCAGGCGGATGACTCCCGGGGTGCGGGCGGAGCTAGCAGGCAAACACACGCACACCCATGCTTGACGAT

Protein Sequence 

>ML1346_ML1346_protein
ISIFQSSHDQSSVWSLRHKMAWKFCGWGG_KQAAFRHRRRLSRACRCTSFDGTFRPVTGLGNRCWERRC_WCTR__CRRICGTSPGRRAR_ASCTSGGLIPGSSTSAHPTKSRVECVGIWPTTSWPSAKRSILSRKSPVTMCTWLGIHRVACSATKLPHTGVRRTSLASWRSAPQLTL_PRFPWVFHQTSAWYLPILWLITSSIAWISQAGWRVPVFRC_IRSRRSKPGSTSCVSCTIVKLCCRVNSSADSLNPKGGSRGRVQQFPSYLSSSLRTIE__RAVLLSTGRW_R_LTSPARCWLSSARLTTSVSQRQCEALDAQHPTPRSTSL_SGQDISAWSWDPGRRSRVGRPSPNGYAG_PLMLTSRRISILCRISRSNTPPVASRLVLGSRTDWGRSPRRRWRWLVAWPMRLWLPTDPFIRWLWRQSGRYHVWLGSDSSMTTLGSR_AVLSANKLTMPHGVSSCCSTDVCILTRLSTGESTTSSEV_SRSGCGRVTA_VC_WKLVPAHWSPLQHCLGWVRLP___GQMPIWPHRSESGERRRS_LTPPILA_YLLTVAS_LVRYWCWVAVSHVICTCRRTPCSKTKSSTWKRSTRMPSTCRPGIGPTRDWLGIWRSSRAARSAASW_LSRSLTTDGRSQLSELPQQPLSIAGTQCIA_RRCITSPRCW_AWAVRSLVVLA_RCRAVYARTDLCTRCVNTASLLYPTPGLCCANLSMTRRLYCTATIRCGCSWAQACRPAYGSGSSKRSRPLMLSNFSLRSTDKLYWLTCRVRRLVARVVRCPALGMSSWVLTTPNRT_SWKTTAVSYRSPTSTRLVCYSLRPAGRSIRLRLSNAVFLLRLTPG_QPSTCYAATTMETIGWRGGVARWFAPHADWFILNQ_PTRSASSLGSTSLRPTVWRWMIVSWRCRR_HCCPERP_RRPT_PKPLPACPSDWGPTLCTWYQS_RSAPPIVQSSVPCARPGFLKRGARYGISIPQVINSGG_LPGCGRS_QANTRTPMLDD

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML1346 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

7 show intermediate predicted evidence for PPIs

82 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML1346

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.