tyrS
mL1352
Probable Tyrosyl-tRNA synthase TyrS (TYRRS)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1612179 – 1613459
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1352_tyrS_dna
CTTCCAGCATCCTTAACGAGCTGGGCTGGCGTGGGTTGGTCGCGCAGTCCACTGACCTCGATGCTCTAGCCGACGAGTTGCGGCGTGGACCGATGACAGTCTACGCCGGTTTCGACCCCACCGCGCCGAGCCTGCATGTCGGACACTTGGTGCCGCTGCTGGTATTGCGGCGCTTTCAACGAGCCGGCCACCGGCCAATCGTGCTAGCGGGCGGGGCAACCGGCATGATTGGTGATCCGCGCGACATCGGTGAGCGCACCCTCAACGAGGCGTACACCGTCGCCGAATGGGCCGAGCGAATCCGCGGACAGCTGGAGCGTTTCGTCGAATTCGACGATGTCGCGAAGTCTAGGAACGGCGCCATCGTTGTCAACAACCTGGAATGGACGAGCCCGATGTCGGCGATCGAGTTCTTGCGCGATGTCGGCAAACACTTTTCGATCAACTTGATGCTAGATCGGGACACAATCCGGCGACGGTTGAATGGCCAAGGGATTTCTTACACGGAGTTCAGCTACATGCTGTTGCAAGCCAACGATTATGCTGAATTGCATCAGCGCCATGGCTGTGCGCTGCAGATCGGCGGTTCGGATCAGTGGGGCAACATCATCGCCGGGGTTCGCCTGGTGCGACAAAAGCTCGGCGCCACAGTGCATGCGCTCACAGTCCCGCTGGTGACCGCTGCCGATGGCGCCAAGCTCGGCAAATCCACCGGAGGTGGCAGTTTATGGTTGGACCCAGAGATGACCAGCCCGTACGCCTGGTACCAATACTTCATCAACACCTCCGACGCTGATGTCATTCGGTACCTGCGTTGGTTCACTTTTTTGTTGCCCGAAGAACTGGTCGAGCTGGAGCAGACGACGGTCTCACGCCCACAGGAACGTGCTGCACAACGTCGACTCGCCACCGAGCTCACGGTTTTGGTGCATGGCGCAGCGGCAACCCAGGCTGTTGAGCATGCCAGCAGGGCATTGTTCGGTCAGGGCGAACTTGCTCGCCTTGACGAAGCGACGTTGGCGACGGCATTGCGCGAGACAGTGGTCGCTGAGCTGAAACCCGGCAATCCCGATGGTATTGTCGATCTGTTGGTGGCCAGCGGTCTGTCCCCTAGCAGGGGTGCGGCGCGGCGCACTATCGATGAAGGCGGGGTGTTGGTCAACAACATTCGCATCCAGAGCGAGGAATGGACGCCCCGGACATCGGATTTCCTGCACGGCCGCTGGCTGGTGCTGCGCCGTGGCAAGCGGAACATCGCCGGGATAGAAAGAGTATAGCACG

Protein Sequence 

>ML1352_TyrS_protein
LPASLTSWAGVGWSRSPLTSML_PTSCGVDR_QSTPVSTPPRRACMSDTWCRCWYCGAFNEPATGQSC_RAGQPA_LVIRATSVSAPSTRRTPSPNGPSESADSWSVSSNSTMSRSLGTAPSLSTTWNGRARCRRSSSCAMSANTFRST_C_IGTQSGDG_MAKGFLTRSSATCCCKPTIMLNCISAMAVRCRSAVRISGATSSPGFAWCDKSSAPQCMRSQSRW_PLPMAPSSANPPEVAVYGWTQR_PARTPGTNTSSTPPTLMSFGTCVGSLFCCPKNWSSWSRRRSHAHRNVLHNVDSPPSSRFWCMAQRQPRLLSMPAGHCSVRANLLALTKRRWRRHCARQWSLS_NPAIPMVLSICWWPAVCPLAGVRRGALSMKAGCWSTTFASRARNGRPGHRISCTAAGWCCAVASGTSPG_KEYST

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding TyrS with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

15 show weak predicted evidence for PPIs

View all pooled AlphaFold results for TyrS

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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