tlyA
mL1358
cytotoxin/hemolysin homologue TlyA
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1618113 – 1618922
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1358_tlyA_dna
CCCGACGTGTCCGCGTTGATGTTGAGCTGGTCCGACGTGGCCTTGCGCGGTCCCGTCAACAGGCCGCGAAATTGATAAGCGCCGGTAAGGTTAGCATCGACGGTTTGCCGGCGGTCAAGCCGAGCACCGCCGTGGCCATAACCACGGTCTTGACCGTCGCGGACGATGGTGAGCGTAGTTGGGTGTCGCGCGGAGCGCACAAACTTATGGGTGCGCTTGACACTTTCGGGATCCCGGTCGCGGGGCGTTGCTGCCTTGACGCTGGCGCGTCCACGGGTGGATTTACTGAAGTTCTGCTGGATCGCGGGGCCGCCGAGGTGGTAGCTGTGGATGTGGGGTACGGTCAGCTGGCCTGGTCGGTGCGCTGCGATCCGCGCGTGATCGTTGTCGAACGGACCAATGTGCACGACTTGTCACCCGAGCTGATCGGCGGGCCGGTTGATTTGGTGGTGGCTGACCTGTCGTTCATTTCATTAGCCACCGTCTTGTCGGCGCTGGCTGGCTGCGCATTACCGAGCGCGGATATCGTTCCCATGGTGAAGCCGCAGTTTGAGGTGGGCAAGGGTCAGGTGGGTCCCGGCGGGGTGGTTCGCGACCTGCGGCTTCGAGCAGATTCGGTTCTGGCCGTCGCGCGTCGTGCGACAGAGCTCGGATGGCGCACCATGGATGTGACTGCCAGCTCGCTACCGGGTCTGTCAGGCAACGTCGAATACTTCCTGTGGCTACGCGCTCAGACCGATCTGGAGCTCTCGACCGATGGGCTGGAGGCAGCCGTGCAACGTGCCATCGCAGAAGGCCCGCAGTGACTCC

Protein Sequence 

>ML1358_TlyA_protein
PDVSALMLSWSDVALRGPVNRPRN__APVRLASTVCRRSSRAPPWP_PRS_PSRTMVSVVGCRAERTNLWVRLTLSGSRSRGVAALTLARPRVDLLKFCWIAGPPRW_LWMWGTVSWPGRCAAIRA_SLSNGPMCTTCHPS_SAGRLIWWWLTCRSFH_PPSCRRWLAAHYRARISFPW_SRSLRWARVRWVPAGWFATCGFEQIRFWPSRVVRQSSDGAPWM_LPARYRVCQATSNTSCGYALRPIWSSRPMGWRQPCNVPSQKARSDS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding TlyA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

25 show weak predicted evidence for PPIs

View all pooled AlphaFold results for TlyA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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