engA
mL1372
PROBABLE GTP-BINDING PROTEIN ENGA
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1631874 – 1633262
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1372_engA_dna
TGAGCCAGGATGGCACCTGGAGTGACGAAAGCGACTGGGAACTTGACGATTCGGATCTAGCCGAGTTCGGGCCGGTGGTGGCGGTGGTGGGCAGGCCTAATGTCGGCAAATCGACGTTGGTTAACCGAATTCTGGGCCGGCGCGAAGCGGTGGTGCAGGATGTTCCCGGGGTGACTCGCGACCGAGTCTCCTATGATGCAATGTGGACCGGACGTCGGTTCGTCGTACAGGACACCGGAGGATGGGAACCCGACGCCAAAGGCCTCAAACGGCTGGTGGCGGAGCAGGCGTCGGTGGCCATGCGCACCGCCGACGCGGTGATCCTTGTGGTTGACGTCGGTGTCGGGGCCACTGACGCCGACGAAGCCGCAGCTCGGATTTTGCTCCGCTCGGGTAAGCTGGTATTCTTAGCAGCCAACAAGGTGGACGGCGAAAAGGGCGAATCGGACGCGTCGGCATTGTGGTCGCTGGGACTGGGTGAGCCGCACGCAATCAGTGCGATGCATGGTCGCGGCGTAGCTGACCTGCTTGACAAGGTGCTGGCCGCACTGCCCAACGTGGCTGAATCGACGTCGCTTGACGGCGGTCTTCGGCGTGTGGCGCTCGTCGGCAAGCCCAATGTGGGCAAGAGTTCATTGCTGAACAAGTTGGCAGGTGACCAGCGTTCGGTAGTCCACGAGGCCGCAGGGACGACAGTAGACCCTGTGGACTCACTTATTGAAATGGGCGGCAGGGTCTGGCGTTTCGTCGACACCGCGGGTTTGCGTCGAAAAGTCGGTCAGGCAAGCGGGCACGAATTCTATGCTTCGGTGCGCACTCATGGGGCCATCGATTCGGCCGAAGTGGTGATCATGCTGATCGACGCATCGGAGCCGCTAACGGGACAAGATCAGCGGGTGCTCTCTATGGTTATCGATGCTGGTCGCGCGTTGGTGCTGGCCTTCAATAAGTGGGATCTAGTTGACGAAGATCGGTGCGATCTGCTGGAGCGCGAGATCGATCGTGAGCTGGTGCAGGTGCGTTGGGCGCAACGGGTCAATATCTCCGCCAAGACGGGCCGGGCGGTGCAGAAACTGGTGCCGGCGATGGAAAATTCGCTGGCGTCGTGGGATACCAGAATTGCGACCGGCCCGCTGAACATATGGATTAAGGCAGTGGTGGCGGCGACACCACCCCCGGTGCGCGGTGGCAAGCAGCCGCGCATACTATTCGCTACCCAGGCGACTGCTCGACCGCCGACGTTCGTGCTGTTCACGACTGGTTTTCTGGAAGCCTGCTACCGACGCTTCCTAGAACGTCGGCTACGTGAGACGTTTGGGTTTGAGGGCAGTCCGATCCGGATCAATGTGCGAGTGCGCGAAAAACGGGGACTCAAGCGCCGCTAACTGT

Protein Sequence 

>ML1372_EngA_protein
ARMAPGVTKATGNLTIRI_PSSGRWWRWWAGLMSANRRWLTEFWAGAKRWCRMFPG_LATESPMMQCGPDVGSSYRTPEDGNPTPKASNGWWRSRRRWPCAPPTR_SLWLTSVSGPLTPTKPQLGFCSARVSWYS_QPTRWTAKRANRTRRHCGRWDWVSRTQSVRCMVAA_LTCLTRCWPHCPTWLNRRRLTAVFGVWRSSASPMWARVHC_TSWQVTSVR_STRPQGRQ_TLWTHLLKWAAGSGVSSTPRVCVEKSVRQAGTNSMLRCALMGPSIRPKW_SC_STHRSR_RDKISGCSLWLSMLVARWCWPSISGI_LTKIGAICWSARSIVSWCRCVGRNGSISPPRRAGRCRNWCRRWKIRWRRGIPELRPAR_TYGLRQWWRRHHPRCAVASSRAYYSLPRRLLDRRRSCCSRLVFWKPATDAS_NVGYVRRLGLRAVRSGSMCECAKNGDSSAANC

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EngA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

4 show intermediate predicted evidence for PPIs

40 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EngA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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