ppm1b
mL1441c
Polyprenol-monophosphomannose synthase Ppm1b
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1734473 – 1736407
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1441c_ppm1b_dna
ATCTATGGTTGATGAAATCATCGAGATTGACCCAGTCGATGACGACCCGGTGAACGGCGCCTTCGCTACGCTTGCGGTACCCAGCCGGGTCGTTAAGCTGCGTGCCACAGTGTGTCACGCACTCGCGCAAATGGGTGTTGCGACGGTAGCACGGGTACCCGCTACCTGGGCTATGCTGGTGCCGCGTCTGCCACGGCTGGTTGTTGCCGTGGTGGCCGGTTTGCTGTTTTGCGCCAGCTTCCCGTCGCTGAACTGGTGGTGGGCCGCCGTTGTCGCCTTCGCGCTGCTGGCTTGGGTCTTGACGCACCCAACTACGACACCTGTAGGTGGTCTGGGCTATGGATTTCTGTTCGGGTTAGCGTTCTATCTGCCGTTGTTGTCGTGGATCAGCAGTCTTGTGGGTGCCACGCCCTGGTGGGCGCTGGCGACCGCAGCCGCGTTTTTGCCCGGTTTTTTTGGCCTGCTCGCTGTCGTAGTGGGCCCGCTGCCGGGTTGGCCGATCTGGTTTGCGGTGGTGTGGGCGGCGCAAGAGTGGTTGAAGTCGGTCGTTCCGTTCGGCGGCTTTCCCTGGGGGTCGGTGGCCTTCGGCCAAGCCGATGGCCCGTTACTGCCATTGGCTCAACTCGGTGGCGCTCCGTTGCTCTCGATGGCGATTGTGCTGGTGGGATGCAGCACTACCGCGATCGCATTAGAAGTCGTTAAGTGGTGGCGAAGCAGTGGTCAGTCGAATAGAAGCGATCCACCGCCGGCGGTGGTGCTGCCAGGTGTTTGTGTGTGCCTGGTGTTGCTGGCCGTCGTCGTTGTTTGGCCCCAGGTGCGGCACGCGGGTGCAGGATCGGGCGGCGAACCTGTGATTACTGTCGCGGCAGTACAGGGCAACGTACCGCGGCTCGGTCTTGACTTCAACGCGCAACGCCGAGCTGTGCTGGACAACCACGTCCATGAGACGCTGCGACTGGCCGAGGACGTGCGTGCTGGAATCGTCCCGCAACCTCAATTCGTGATCTGGCCCGAGAATGCGTCGGATATCGATCCACTAGTCAATGGCGATGCTGGGCAAGAGATCACGGTGGCGGCCGCGACGATTGACGCGCCGATCTTAGTCGGCACCGTGCTTGATGTCCAAGGCCCTGTACCACAAGCCCCCGAGTACACCAATACAGTGATTGTCTGGAATCCTGGCACCGGACCGGCTGATCGCCATGACAAGGAAATTGTGCAACCTTTCGGCGAGTATTTGCCGATGCCGTGGCTTTTTAAGCGTCTTTCTAAGTATGCCGACCGGGTGAGCCACATCGTGCCCCGCCAAAGTCAAAGTAGTGGTGTCGTGCGTATCGCGGGGGTACCTATCGGGGTGACCACCTGTTGGGAAGTGATCTTTGACCGTGCTGCGCGAAAAGCTGTCCTCAATGGCGCCCAATTGCTGGCGGCGCCCACCAACAACGCTACTTTCAACAAAACGATGAGTGAGCAACAGTTGGCCTTCGCCAAAGTCCGAGCTGTGGAGCACGACCGATATGTGGTGGTTACCGGCACCACCGGGATCAGCTCGGTGATTGCGCCGGACGGCAGCGAATTGGTCCGCACCGACTTCTTTGTGCCCGCATATCTGGACATGCAGGTGCGTCTTAAGGCGAAGCTGACTCCAGCAACTTGCTGGGGTCTGACCTTGCAGTGGATCCTAGTCGGAACGGCTGGAGCGATCGTGCTCGCCGCCATGCGGCACAATAATGGTTCCCGCTCCCGTATCGTTTTGGGTCTAGGGTCATCGGCGAGTCTGAAGACTCGGGTACGCCAGGCGAATGTTAGGGAGGCGTTGACACTCCGCCTGGGGGATCGACCGCTAATCCACCTGAGCCGGCTGGTGACTACACTCCGCTCTATCTATAAGGGCGGCCAAAAGCCACGTTATTTCGGGCGACACAAAGGAGCTAA

Protein Sequence 

>ML1441c_Ppm1b_protein
IYG__NHRD_PSR_RPGERRLRYACGTQPGR_AACHSVSRTRANGCCDGSTGTRYLGYAGAASATAGCCRGGRFAVLRQLPVAELVVGRRCRLRAAGLGLDAPNYDTCRWSGLWISVRVSVLSAVVVVDQQSCGCHALVGAGDRSRVFARFFWPARCRSGPAAGLADLVCGGVGGARVVEVGRSVRRLSLGVGGLRPSRWPVTAIGSTRWRSVALDGDCAGGMQHYRDRIRSR_VVAKQWSVE_KRSTAGGGAARCLCVPGVAGRRRCLAPGAARGCRIGRRTCDYCRGSTGQRTAARS_LQRATPSCAGQPRP_DAATGRGRACWNRPATSIRDLARECVGYRSTSQWRCWARDHGGGRDD_RADLSRHRA_CPRPCTTSPRVHQYSDCLESWHRTG_SP_QGNCATFRRVFADAVAF_ASF_VCRPGEPHRAPPKSK_WCRAYRGGTYRGDHLLGSDL_PCCAKSCPQWRPIAGGAHQQRYFQQNDE_ATVGLRQSPSCGARPICGGYRHHRDQLGDCAGRQRIGPHRLLCARISGHAGAS_GEADSSNLLGSDLAVDPSRNGWSDRARRHAAQ_WFPLPYRFGSRVIGESEDSGTPGEC_GGVDTPPGGSTANPPEPAGDYTPLYL_GRPKATLFRATQRS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Ppm1b with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

97 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Ppm1b

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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