nadD
mL1454c
PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NICOTINATE MONONUCLEOTIDE ADENYLYLTRANSFERASE) (NAMN ADENYLYLTRANSFERASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1747951 – 1748595
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1454c_nadD_dna
AATCATGGGTGGGACGTTCGACCCCATCCACTATGGTCACCTGGTTGCTGCAAGTGAGGTGGCGCACATGTTTGAACTCGATGAAGTGATGTTTGTGCCCAGCGGGCAGCCTTGGCAAAAGGGTCGGCACGTCTCCGCTGCTGAGGACCGGTACTTGATGACGGTGATCGCAACCGCGTCCAATCCGCGTTTCTCGGTGAGCAGAGTCGACATCGACCGCACCGGCCCCACCTACACCAGGGATACGGTGCACGATCTGCATGCCCTCAACCCTGACTCCGAACTGTACTTCATTACCGGCGCCGACGCGCTGGCTTCCATTCTGTCTTGGCAAGGTTGGGACGAGCTTTTCGACTTGGCGCGATTCGTCGGGGTCAGCCGACCCGGATATGAGCTGGGCCAAGAGCACATCACCGGGGTTATGGGCGAGCTGCCCGCAGACGCGTTGACATTGGTCGAAATCCCGGCGCTGGCGATCTCGTCGACCGACTGCCGGCAACGTGTCGAGCAGCGTCAACCGCTGTGGTATCTGATGCCCGACGGTGTCGTGCAGTACGTGTTCAAGCGCCGACTCTATCGTGGACCTCACGGCGTGGCTGGGACTGGGCGCTTAACGACGCCCAGTCTGGTCGTCGGAAACAACAC

Protein Sequence 

>ML1454c_NadD_protein
NHGWDVRPHPLWSPGCCK_GGAHV_TR_SDVCAQRAALAKGSARLRC_GPVLDDGDRNRVQSAFLGEQSRHRPHRPHLHQGYGARSACPQP_LRTVLHYRRRRAGFHSVLARLGRAFRLGAIRRGQPTRI_AGPRAHHRGYGRAARRRVDIGRNPGAGDLVDRLPATCRAASTAVVSDARRCRAVRVQAPTLSWTSRRGWDWALNDAQSGRRKQH

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding NadD with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

3 show intermediate predicted evidence for PPIs

23 show weak predicted evidence for PPIs

View all pooled AlphaFold results for NadD

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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