proA
mL1458c
PROBABLE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE PROTEIN PROA (GPR) (GLUTAMATE-5-SEMIALDEHYDE DEHYDROGENASE) (GLUTAMYL-GAMMA-SEMIALDEHYDE DEHYDROGENASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1751755 – 1752984
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1458c_proA_dna
CAACTTGCGTCAAGAAGTCCACGATGCTGCCCGGCGAGCCCGGGTCGCTGCTCGCGCTCTCGCAGTTATGCCGACGGTAGCTAAGGACCATGCACTGCGGGCCGCAGCAACGGCGGTAACTGCTCACACCGAGGAGATCCTCGCGGCCAACGCCGAAGATCTGCAGGCGGCTCGGGCCACCGACACACTGGCCGCGACGCTCGACAGGTTAGCTTTGGATAGGCAACGCATTGACCAAATCGCGGGCGGTTTGCGTCAAGTCGCGGCGTTGCCCGACCCGATCGGGGAGGTGTTGCGCGGTTACACGCTACCTAATGGGCTGCAGTTGCGCCAGCAGCGGGTTCCACTCGGCGTAGTGGGTATGATCTACGAGGGCCGGCCTAACATCACCGTTGACGCTTTCGGACTGGCGTTCAAGTCAGGTAATGCGGCGTTGCTGCGTGGCAGCTCGTCAGCGGCGAAGTCCAACCAAGCGCTCGTAGAGGTGTTGCACGCTGCGTTGGTTAGCGAAGACTTGCCCGCCGACGCGGTCCAGCTGCTTTCAGCTGCCGATAGATCCACGGTCACCCACCTGATCCAAGCTCGCGGCCTGGTGGATGTGGTGATCCCGCGCGGGGGAGCGAACCTGATTGATGCGGTGGTCCGTGACGCGCAAGTGCCTATTATCGAGACCGGTGTCGGCAACTGTCACGTCTACGTGCATCAGGCTGCTGACCTGGAGGTTGCCGAACGGATCCTGCTGAACTCCAAGACCCGTCGGCCCAGTGTCTGCAATGCTGCCGAGACGCTGTTGATCGATGCAGCGATTGCCGATCACACTATGCCTAGGTTGGTCGCTGCCTTGCAAGGTGCCGGAGTAACGGTGCACGGTGGTCTTTCGGGAGACCCGGACAAGGCTGACCTGTGTCGCGAATACCTGTCGATGGACATTGCCGTGGCGGTGGTCGATGGCGTCGACGCCGCAATTGCCCACATCAATGAGTACGGCACCGGACACACCGAGGCGATTGTGACCACCAATATGGCTGCCGCCCAACGGTTTGCCGACGGAGTGGACTCGGCCACGGTGATGGTCAACGCATCGACGGCGTTCACTGATGGTGGGCAGTTCGGTTTCGGCGCCGAGATCGGTATCTCCACCCAGAAATTGCATGCCCGTGGACCAATGGGACTGTCGGAAATGACCTCGACTAAGTGGATCGTGTGGGGAGACGGTCAGATCCGACCGGC

Protein Sequence 

>ML1458c_ProA_protein
QLASRSPRCCPASPGRCSRSRSYADGS_GPCTAGRSNGGNCSHRGDPRGQRRRSAGGSGHRHTGRDARQVSFG_ATH_PNRGRFASSRGVARPDRGGVARLHAT_WAAVAPAAGSTRRSGYDLRGPA_HHR_RFRTGVQVR_CGVAAWQLVSGEVQPSARRGVARCVG_RRLARRRGPAAFSCR_IHGHPPDPSSRPGGCGDPARGSEPD_CGGP_RASAYYRDRCRQLSRLRASGC_PGGCRTDPAELQDPSAQCLQCCRDAVDRCSDCRSHYA_VGRCLARCRSNGARWSFGRPGQG_PVSRIPVDGHCRGGGRWRRRRNCPHQ_VRHRTHRGDCDHQYGCRPTVCRRSGLGHGDGQRIDGVH_WWAVRFRRRDRYLHPEIACPWTNGTVGNDLD_VDRVGRRSDPTG

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ProA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

1 shows weak predicted evidence for PPIs

View all pooled AlphaFold results for ProA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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