rne
mL1468c
possible ribonuclease E Rne
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1765045 – 1767819
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1468c_rne_dna
ATACGTGATAGACGGTGCACCCCCGTTAGAGCCATCAAAAGAGCCGACGCAGCATATGGAACTGCCGGACCGCTTGAGAGTCCATTCGCTAGCACGAACGTTGGGAACCACCAGCAGACGAGTGTTGGACGTGCTGAGCGCTCTCGACGGCCGGATCCGTAGCGCACATTCCAGTGTCGACCGCGTCGACGCGGTCCGGGTCCGTGATCTGCTGGCCAGCCAACCCAACTCACCTCATGAACTCACTGCCGTACCTGATAACCCTGTCGCGCTCGAAGAGCGCGACTCTCGGCTGGTGCTAGAAACCACAGTAGAGCGGCCGCACTACATGCCGTTGTTCGTTGCGCCACAGCCGATAGAGGTCGATGATGACTCCTGCGCTGACGATGATGTGGAATCCGGTGACGACTCCGACGTTGGCGACGACGAAGAGCAACCCGATCGACCGGCGAACCGTCGTCGGCGTCGTGGCCGTCGGGGTCGTGGTCGGGGCCGCGGTGAGCAGGGTGGATCCGACGTCCAGAGCGACGATGTCGACGGCGCGGTCGACTCAACCGAGTCTGAGGACTTCGATGGCCAAGATTTCGACGAGTCCGAAGACACCGAAATCGGTTACGACGAGAGTGGGTCCTCTGAAGCCGGCAACCGCCGCCGCCGTCGGCGCCGACGTCGTAAGTCGGGGGTAGGTGAAGACGAGGGGTGCGCGCCCGACGATCCGCCGAACACGGTTGTGCACGAACGGACACCCCGTGCGGCTGGTCGGTCTGCTAGTTTTGACAACGGCGTCAACGGCACGGGCAGCGCCGATATCAAGGGTATCGACGGTTCGACTCGACTGGAGGCCAAGCGGCAACGCCGCCGAGACGGGCGCGACGCCGGGCGGCGCCGTTCATCAGTGTTGAGCGAGGCCGAATTCCTGGCTCGGCGCGAGTCCGTCGAGCGGGTCATGGTGGTGCGCGATCGGATCCGCACTGAGCCGCCCCACCCTGGCGCTCGATACACCCAGATCGCGGTGCTCGAAGACGGCATCGTCGTCGAGCACTTCGTGACGTCGGCAGCATCTGCTTCCCTGGTCGGCAACATCTACCTCGGTATCGTGCAGAACGTGCTGCCGTCGATGGAGGCGGCCTTCGTTGACATCGGTCGCGGTCGCAACGGCGTGCTTTATGCCGGAGAAGTAAACTGGGAAGCGGCCGGATTGGGCGGGGCCGATCGCAAGATTGAACAGGCCCTCAAACCCGGCGACTATATCGTTGTCCAGGTCAACAAGGACCCGGTCGGGCACAAAGGGGCGCGACTTACCACGCAAGTGTCTTTGGCCGGTCGTTACCTGGTTTACGTCCCAGGGGCGTCGTCGACCGGGATCAGCCGTAAGCTGCCTGACACCGAACGCCAGCGCCTCAAGGAGATCCTGCGTGAGGTAGTGCCACCCGATGCGGGCGTGATCATCCGCACTGCGTCAGAGGGCGTCAAAGAGGAAGACATCCGCAAGGATGTCACCCGCCTGCAGGAGCACTGGGAACAGATCGAAGCCAAGACAATCCAGACCAAGGAAAAGGCCGCTGGCGCTGCGGTGGCCCTTTATGAGGAACCGGATGTGTTGGTCAAAGTCATCCGCGACTTGTTCAATGACGACTTCTCGGGCCTCGTCGTCTCCGGCGACGAGGCATGGAATACCATCAATGAGTATGTGAATTCTGTTGCTCCCGAACTTGTTTCGAAGTTGACAAAGTATGACCCGCCAATCGGTCCGGACGGGCAGCACGGGCCAGATGTCTTCGCGGTACATCGCATCGACGAGCAATTGGCCAAGGCAATGGACCGGAAAGTGTGGCTGCCATCGGGCGGTACACTGGTGATTGACCGGACTGAGGCGATGACGGTGATCGACGTCAATACTGGCAAGTTCACCGGGTCTGGGGGTAACCTCGAGCAGACAGTCACCAAGAATAATCTTGAGGCAGCTGAGGAGATCGTGCGCCAGCTGCGGCTGCGTGATATTGGCGGCATCGTGGTCATCGACTTCATCGATATGGTGCTCGAGTCCAACCGCGACTTGGTGTTGCGTCGACTGACTGAGGTGCTTGCTCGCGACCGCACTCGTCACCAGGTGTCCGAGGTGACGTCTTTGGGGCTGGTGCAATTGACCCGCAAACGGTTGGGCACCGGGCTGGTCGAGGCGTTCTCGACATCGTGTCCGAACTGCACAGGTCGCGGTATCCTGCTGCACACCGACCCAGCTAATTCGACCCCGATGGTTGGACGCAAGTCCGAGTCAGGCGGTCGGCGAAGTAAGCGATCGAAAAAGAACCGATCGGACGAGACCGCTGTGGTTAAAGTACCGGTGCATGCTCCGGGCGAGCATCCGATGTTTAAGGCGATGGCCGCGGGCTCGTCCTCGGTGGTTGTTGGTGGCGAGGACGAATCCAACGAGTCTGGTACAGAACTCACCGGGAAGATCGACGAGCCGCTCGAAGAGCAGGCTGTTGCTGGCCTAGATGATGTTGACCAGGAAGATTTCGACACCGACGAAGAAGACGACCTCGACGATGACGAGGAGCTCGACGACGAGGAAGACCTTGGCGACGATGACGAGGAACTCGATTTAGACGACGATCTTGACGTTGACGAAGACGAGTCTGACTCCGAGGCCGACCTCGACAGCGCTGACGTGCTTGACCGCTCCACTCTCCTGATCAGAAACAGATCAGGTTTTGCCCGTCCGCGACGGCGGCGCGCAGCGGGTCGTCCGGCCGGGCCGCCGATCCACGTGGA

Protein Sequence 

>ML1468c_Rne_protein
IRDRRCTPVRAIKRADAAYGTAGPLESPFASTNVGNHQQTSVGRAERSRRPDP_RTFQCRPRRRGPGP_SAGQPTQLTS_THCRT__PCRARRARLSAGARNHSRAAALHAVVRCATADRGR__LLR_R_CGIR_RLRRWRRRRATRSTGEPSSASWPSGSWSGPR_AGWIRRPERRCRRRGRLNRV_GLRWPRFRRVRRHRNRLRREWVL_SRQPPPPSAPTS_VGGR_RRGVRARRSAEHGCARTDTPCGWSVC_F_QRRQRHGQRRYQGYRRFDSTGGQAATPPRRARRRAAPFISVERGRIPGSARVRRAGHGGARSDPH_AAPPWRSIHPDRGARRRHRRRALRDVGSICFPGRQHLPRYRAERAAVDGGGLR_HRSRSQRRALCRRSKLGSGRIGRGRSQD_TGPQTRRLYRCPGQQGPGRAQRGATYHASVFGRSLPGLRPRGVVDRDQP_AA_HRTPAPQGDPA_GSATRCGRDHPHCVRGRQRGRHPQGCHPPAGALGTDRSQDNPDQGKGRWRCGGPL_GTGCVGQSHPRLVQ_RLLGPRRLRRRGMEYHQ_VCEFCCSRTCFEVDKV_PANRSGRAARARCLRGTSHRRAIGQGNGPESVAAIGRYTGD_PD_GDDGDRRQYWQVHRVWG_PRADSHQE_S_GS_GDRAPAAAA_YWRHRGHRLHRYGARVQPRLGVASTD_GACSRPHSSPGVRGDVFGAGAIDPQTVGHRAGRGVLDIVSELHRSRYPAAHRPS_FDPDGWTQVRVRRSAK_AIEKEPIGRDRCG_STGACSGRASDV_GDGRGLVLGGCWWRGRIQRVWYRTHREDRRAARRAGCCWPR_C_PGRFRHRRRRRPRR_RGARRRGRPWRR_RGTRFRRRS_R_RRRV_LRGRPRQR_RA_PLHSPDQKQIRFCPSATAARSGSSGRAADPRG

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Rne with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

61 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Rne

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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