valS
mL1472c
PROBABLE VALYL-tRNA SYNTHASE PROTEIN VALS (VALYL-tRNA SYNTHETASE) (VALINE--tRNA LIGASE) (VALINE TRANSLASE) ELONGS TO CLASS-I AMINOACYL-TRNA SYNTHETASE FAMILY.
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1770444 – 1773104
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1472c_valS_dna
ACCGGTGACCACCAGCCCTAGTTCCTCTGCTGACCTGCTGCCCAAGTCGTGGGACCCAGGTGCGATGGAGAGCGTGATTTACCAGAAGTGGTTGAACTCCGGTTACTTCGCCGCGGATCCCGCCAGCACAAAACCTGGGTATTCGATCGTGCTTCCGCCTCCTAATGTGACCGGCAGTCTGCATATGGGCCACGCGTTAGAGCACACCATGATGGACGCCTTGACTCGCCGCAAACGGATGCAGGGATATGAGGTGTTATGGCAGCCAGGCATGGACCACGCAGGGATCGCGACTCAGAGTGTAGTGGAAAAACAGCTTGCGATCAACGGCAAGATCAAGGAGGACTTTGGTCGGGAGCTGTTTGTCGACAAGGTGTGGGACTGGAAGCGTGAATCCGGCGGTGCCATAGCCGGCCAGATGCGCCGGCTCGGTGATGGGGTGGATTGGAGCCGCGACCGGTTCACTATGGATGACGGCTTATCGCGGGCGGTGCGGATGATCTTCAAGCGGCTCTACGACGCCGGGCTGATCTACCGGGCGGAGCGGCTGGTCAACTGGTCGCCGGTACTTCGGACGGCACTCTCCGACATCGAGGTTATCTACGACGAGATCGAGGGCGAATTGATCTCGTTCCGCTATGGGTCACTCGACGACGACGAGCCACACATCGTGGTAGCTACCACCCGGGTCGAGACGATGCTCGGCGACACCGGGATCGCCGTGCATCCCGATGACAAGCGCTATCAGCATCTGGTCGGGACTACGCTGCCGCACCCGTTTATCGACCGCGAACTTGTAATCGTAGCTGATGAGCACGTCGACCCTGAATTCGGCACCGGCGCCGTCAAAGTCACACCCGCTCATGATCCCAACGACTTTGAAATCGGATTGCGGCACAACCTGCCGATGCCGAACGTCATGGACGTTAAGGCCGTTATCGTTGACACCGGAACTGAATTCGACGGCATGGATCGATTCGAGGCCCGCATCGCGGTGCGCGAAGCGCTAGCGGTGCAGGGCCGCATTGTCGAGGAGAAACGACCCTACCGGCACAGCGTGGGCCATTCTGAGCGCAGCGGCGAGGTCATCGAGCCACGCCTGTCGCTGCAATGGTGGGTCAGGGTGGAATCGCTGGCCAAGGCCGCTGGTGACGCGGTGCGTAACGGGGACACCGTGATTCACCCTGCTAGCATGGAATCGCGCTGGTTCGCTTGGGTGGACGACATGCGCGACTGGTGCATCTCACGGCAGCTGTGGTGGGGCCATCGCATACCGATCTGGTACGGTCCCAACGGGGAACAAGTGTGTGTCGGTCCCGACGAGACCCCTCCGGAGGGCTGGCAACAGGACCCCGACGTGCTGGACACCTGGTTCTCGTCCGCGTTGTGGCCGTTTTCCACGCTGGGCTGGCCACAAATGACTCCGGAGCTGGAAAAATTCTATCCGACAAGTATTCTCGTCACCGGCTATGACATTCTGTTTTTCTGGGTAGCGCGCATGATGATGCTCGGCACCTTCGTCGGCGGGGACGATGCCATCACACTGGGTGGCTGCCGTGGCCCGCAGGTGCCGTTCACCGATGTCTTCCTGCATGGGCTGATCCGCGACGAATTCGGTCGCAAGATGAGTAAGTCCAGGGGTAACGTCATCGACCCGCTGGCCTGGATGGATATGTTCGGAGCTGACGCGCTGCGCTTCACTCTGGCACGCGGCTCCAGCCCCGGTGGTGATCTGGCTATAGGAGAGGATCACGTCCGCGCGTCGCGCAACTTCGGTACCAAGCTGTTCAACGCCACCCGGTACGCACTGCTCAATGGTGCTGCGCTGGTACCTTTGCCTGCGCTGACGGCGCTGACAGATGCCGACCGCTGGATTCTCGGAAGGCTGGAACAGGTTCGCGCCGAAGTTGATTCAGCTTTCGATGGCTACGAATTCAGCCGCGCCTGCGAGGCGCTCTACCATTTTGCGTGGGACGAATTCTGCGACTGGTATCTCGAATTGGCCAAGGCACAGCTTGCTGACGGGCTCACGCACACCACAGCAGTGCTGGCCGCGGCACTCGATACGTTGCTGCGGTTGCTGCACCCGGTGATGCCGTTTATTACCGAAACGCTCTGGCAGGCACTGACCCAACTGGAGTCACTAGTGATTGCTACCTGGCCGGAGCCTTCTGGCATCAGCCTAGATCTGGTTGCCGCGCAGCGGATCAGCGATATGCAGAAGCTGGTGACCGAGATCCGTCGGTTCCGTAGTGATCAGGGGTTGGTCGATCGACAGAAGGTGCCGGCTCGATTGTCTGGTGTCGAAGATTCCGACCTGGCCACCCAGGTGGGCTTCGTGACATCACTAGCTTTGCTTACTGCTGCGAGCAACGATTTTCGCCCTTCAGCGTTGCTGGAGGTTCGTCTCGGCCCTAACAAAGACCGCGCCGTCGTCGTTGAACTCGACACTTCGGGCACCATCGATGTGGCTGCCGAGCGTCGTCGCATGGAAAAGGACTTGGCTGCAGCGCAAAAAGAGCTGGCATCGACCGCCGCAAAGTTGGCCAACGCGGACTTTCTAGCTAAAGCCCCGGAAGCAGTCGTTGTCAAAATCCGCGATCGTCAGCGGATGGCTAAGGAAGAAACCGACCGCATCATCGCTAGGCTGGCTGGGCTGCA

Protein Sequence 

>ML1472c_ValS_protein
TGDHQP_FLC_PAAQVVGPRCDGERDLPEVVELRLLRRGSRQHKTWVFDRASAS_CDRQSAYGPRVRAHHDGRLDSPQTDAGI_GVMAARHGPRRDRDSECSGKTACDQRQDQGGLWSGAVCRQGVGLEA_IRRCHSRPDAPAR_WGGLEPRPVHYG_RLIAGGADDLQAALRRRADLPGGAAGQLVAGTSDGTLRHRGYLRRDRGRIDLVPLWVTRRRRATHRGSYHPGRDDARRHRDRRASR_QALSASGRDYAAAPVYRPRTCNRS__ARRP_IRHRRRQSHTRS_SQRL_NRIAAQPADAERHGR_GRYR_HRN_IRRHGSIRGPHRGARSASGAGPHCRGETTLPAQRGPF_AQRRGHRATPVAAMVGQGGIAGQGRW_RGA_RGHRDSPC_HGIALVRLGGRHARLVHLTAAVVGPSHTDLVRSQRGTSVCRSRRDPSGGLATGPRRAGHLVLVRVVAVFHAGLATNDSGAGKILSDKYSRHRL_HSVFLGSAHDDARHLRRRGRCHHTGWLPWPAGAVHRCLPAWADPRRIRSQDE_VQG_RHRPAGLDGYVRS_RAALHSGTRLQPRW_SGYRRGSRPRVAQLRYQAVQRHPVRTAQWCCAGTFACADGADRCRPLDSRKAGTGSRRS_FSFRWLRIQPRLRGALPFCVGRILRLVSRIGQGTAC_RAHAHHSSAGRGTRYVAAVAAPGDAVYYRNALAGTDPTGVTSDCYLAGAFWHQPRSGCRAADQRYAEAGDRDPSVP__SGVGRSTEGAGSIVWCRRFRPGHPGGLRDITSFAYCCEQRFSPFSVAGGSSRP_QRPRRRR_TRHFGHHRCGCRASSHGKGLGCSAKRAGIDRRKVGQRGLSS_SPGSSRCQNPRSSADG_GRNRPHHR_AGWAA

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ValS with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

72 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ValS

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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