clpX
mL1477c
PROBABLE ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1779777 – 1781057
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1477c_clpX_dna
CATCATGGCGCGTATCGGAGACAGCGGTGACTTGCTGAAGTGCTCGTTTTGCGGGAAGAGTCAGACTCAGGTCAAGAAACTAATTGCGGGCCCTGGGGTGTACATCTGTGATGAATGTATTGACCTGTGCAACGAGATCATCGAAGAAGAACTGGCCGATGCTGACGATGTGCAGCTTGATGAGCTGCCCAAGCCTGTTGAGATTCGGGAGTTTCTTGAGGGTTACGTCATCGGGCAGGACACCGCCAAGCGGACGTTGGCTGTCGCGGTCTATAATCACTACAAGCGGATCCAGGCTGGAGAGAAGGGCCGTGACTCTAAGCGCGAACCGGTAGAGTTGGCCAAATCCAACATCTTGATGCTGGGACCTACTGGTTGCGGCAAGACTTACCTGGCTCAGACGTTGGCCAAGATGCTCAATGTCCCGTTCGCCATCGCCGACGCCACCGCACTGACCGAGGCCGGTTACGTCGGTGAGGATGTCGAGAACATCTTGCTTAAGCTGATCCAGGCCGCCGACTATGACGTCAAGCGTGCCGAGACCGGTATTATTTACATCGATGAGGTCGACAAGATCGCTCGTAAGAGTGAGAACCCATCGATCACTCGTGACGTCTCCGGCGAGGGCGTTCAACAAGCCCTGCTGAAAATTCTAGAAGGTACCCAAGCGTCGGTTCCCCCGCAAGGTGGCCGCAAGCACCCACACCAAGAATTCATTCAGATCGATACCACCAACGTGTTGTTCATCGTCGCCGGTGCCTTTGCCGGGTTGGATAAGATTATTTACGAGCGTATTGGCAAACGCGGCTTAGGCTTTGGTGCCGAAGTCCGCTCCAAAGCCGAAATCGACACCACCGATCATTTCGCCGATGTGATGCCTGAAGATCTGATCAAGTTCGGCTTGATCCCTGAGTTCATCGGACGACTCCCGGTGATCGCCTCGGTCATCAATCTGGACATGGAGTCGTTGGTCAAGATCCTGTCCGAACCGAAGAACGCTTTGGTCAAGCAGTACACTTGGCTTTTCGAAATGGACGGTGTGGAGCTGGAATTCACTAACGACGCGCTGGAAGCGGTCGCCGACCAAGCAATCCACCGCGGCACCGGCGCTCGTGGCCTGCGGGCCATCATGGAAGAAGTCCTGCTACCCGTGATGTATGATATTCCTAGCCGCGATGACGTTGCCAAAGTGGTGGTGACCAAGGAGACTGTGCAGGACAACGTGTTGCCGACAATCGTGCCGCGCAAGCCGTCGCGCACTGAGCGCCGCGATAAGAGTGC

Protein Sequence 

>ML1477c_ClpX_protein
HHGAYRRQR_LAEVLVLREESDSGQETNCGPWGVHL__MY_PVQRDHRRRTGRC_RCAA__AAQAC_DSGVS_GLRHRAGHRQADVGCRGL_SLQADPGWREGP_L_ARTGRVGQIQHLDAGTYWLRQDLPGSDVGQDAQCPVRHRRRHRTDRGRLRR_GCREHLA_ADPGRRL_RQACRDRYYLHR_GRQDRS_E_EPIDHS_RLRRGRSTSPAENSRRYPSVGSPARWPQAPTPRIHSDRYHQRVVHRRRCLCRVG_DYLRAYWQTRLRLWCRSPLQSRNRHHRSFRRCDA_RSDQVRLDP_VHRTTPGDRLGHQSGHGVVGQDPVRTEERFGQAVHLAFRNGRCGAGIH_RRAGSGRRPSNPPRHRRSWPAGHHGRSPATRDV_YS_PR_RCQSGGDQGDCAGQRVADNRAAQAVAH_APR_EC

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ClpX with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

19 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ClpX

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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