clpP1
mL1480c
PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1782849 – 1783523
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1480c_clpP1_dna
GTGCGTGATCGCCAAACAACGGGCTCGGTTCGTTAGTGTCGGTGCATACAGAACTCCAGAAAGCAGGTATCCCACTGTGGGCCACGTGACTGACATCCGTTCGAATTCGCAGGGTTTCAACCTCACGGACTCGGTCTATGAGCGATTGCTCTCCGAACGCATCATCTTCCTGGGGTCGGAGGTGAACGACAACATCGCCAATCGGCTCTGCGCACAGATACTGCTGCTTGCCGCCGAAGACGCCTTCAAGGACATTTCTCTGTACATCAATTCCCCCGGTGGATCGATCAGCGCCGGGATGGCGATCTACGACACCATGGTGCTGGCGCCATGTGACATCGCCACCTACGCGATGGGCATGGCCGCGTCGATGGGGGAGTTCTTGCTGGCGGCGGGAACTAGGGGCAAGCGCTACGCGCTACCACACGCCCGCATCCTAATGCACCAGCCGCTGGGCGGGGTGACCGGCAGTGCAGCCGACATCGCCATCCAGGCTGAGCAGTTCGCCGTCATCAAAAAGGAGATGTTCCGGCTCAACGCTGAGTTCACCGGTCAGCCGATCGAGCGAATCGAAGCGGATTCTGACCGCGACCGCTGGTTCACTGCCTCGGAAGCCCTGGAATACGGTTTTGTCGACCACATCATTACCCGCGCCCACGTCAACGGAGAAGTGCA

Protein Sequence 

>ML1480c_ClpP1_protein
VRDRQTTGSVR_CRCIQNSRKQVSHCGPRD_HPFEFAGFQPHGLGL_AIALRTHHLPGVGGERQHRQSALRTDTAACRRRRLQGHFSVHQFPRWIDQRRDGDLRHHGAGAM_HRHLRDGHGRVDGGVLAGGGN_GQALRATTRPHPNAPAAGRGDRQCSRHRHPG_AVRRHQKGDVPAQR_VHRSADRANRSGF_PRPLVHCLGSPGIRFCRPHHYPRPRQRRSA

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ClpP1 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

11 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ClpP1

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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